Congenial infection is one of the greatest diagnostic challenges facing clinicians. The list pathogens related to intrauterine infections continues to grow with the identification of new etiologies and resurgence of others. Identification of a congenital infection as early as possible has both diagnostic and therapeutic advantages. This article will give an overview on common clinical findings ...

Congenital infection with cytomegalovirus (CMV) is the main cause of sensorineural hearing loss and psychomotor impairment which can develop at birth or later in infant's life. Because of a lack of nation-wide serological screening for pregnant women and accepted antiviral therapy during pregnancy in a high seroprevalence rate population of Poland, we introduced the regional screening programme...

Possible relation of prenatal infections with various congenital malformations was examined in 194 cases including newborns, fetuses, and stillbirths. 92 children had various isolated congenital malformations; 38 – multiple malformations; and 64 – autosomal trisomy. Clinical data, case history and gross anatomy protocols were analyzed for all patients. Subspecialty consultation, radiological an...

We report two cases of pulmonary hypoplasia due to fetal ascites in symptomatic congenital cytomegalovirus (CMV) infections despite fetal therapy. The patients died soon after birth. The pathogenesis of pulmonary hypoplasia in our cases might be thoracic compression due to massive fetal ascites as a result of liver insufficiency. Despite aggressive fetal treatment, including multiple immunoglob...

INTRODUCTION Unilateral absence of the pulmonary artery (UAPA) or pulmonary artery agenesis is a rare congenital disorder presenting with a wide spectrum of symptoms. The clinical presentation is variable and many patients can be asymptomatic for many years and even throughout their lives. CASE PRESENTATION We report the case of a 53-year-old African-American woman who was diagnosed with righ...

BACKGROUND Cytomegalovirus (CMV) is a common cause of congenital infection worldwide and infants with symptomatic congenital CMV (cCMV) infection are at significantly increased risk of developing adverse long-term outcomes. This study aimed to determine the prevalence of cCMV infections in symptomatic infants under 3 weeks in Tehran, IRAN and to evaluate the usefulness of serologic markers in t...

Despite the fact that term aphantasia was coined only 6 years ago, such fascinating neurological condition has captured imagination of neuroscience community. The is congenital in most cases but can be very distressing when suddenly acquired. authors report a case acquired following mild COVID-19 hoping to raise awareness possibility uncommon neuropsychological syndromes follow infections.

The term congenital neutropenia encompasses a family of neutropenic disorders, both permanent and intermittent, severe (<0.5 G/l) or mild (between 0.5-1.5 G/l), which may also affect other organ systems such as the pancreas, central nervous system, heart, muscle and skin. Neutropenia can lead to life-threatening pyogenic infections, acute gingivostomatitis and chronic parodontal disease, and ea...

Evidence that prevention, diagnosis and treatment of toxoplasmosis is beneficial developed as follows: anti-parasitic agents abrogate Toxoplasma gondii tachyzoite growth, preventing destruction of infected, cultured, mammalian cells and cure active infections in experimental animals, including primates. They treat active infections in persons who are immune-compromised, limit destruction of ret...