Background: Congenital heart diseases, which are asymptomatic at birth, are the most important causes of infant mortality. This study aimed to evaluate the role of pulse oximetry in the early detection of congenital heart diseases among newborns.Methods: In this cross-sectional descriptive study, 1230 newborns who were born in university hospitals in an urban area of Iran were placed unde...

proximity of the vagus nerve to a patent ductus arteriosus (pda) can cause traction or entrapment of vagus nerve during surgical closure of the in rare occasions. this can lead to a life threatening postoperative bradycardia. herein, we report a case of bradycardia caused by unexpected irritation of the vagal trunk by the end of operation. the patient was managed by re-opening the chest, lung r...

now-a-days truncus arteriosus has been known as “common arterial trunk” (cat) and is an uncommon congenital cardiac defect presenting in about 1-3% congenital heart disease. environmental and genetic factors effects on incidence of cat and other conotruncal anomalies. the majority patients with cat and 22q11 deletion have other anomalies such as hypoplasia or aplasia of the thymus or parath...

holt-oram syndrome (hos) is a developmental disorder inherited in an autosomal-dominant pattern. affected organs are the heart and forelimbs with upper extremity skeletal defects and congenital heart malformation. in this study we present three cases of hos in the same family. in one of these three individuals we detected a transition of c to t (ctg-gtt, v205v) in exon 7 of the tbx5 gene. this ...

objectives we investigated the menstrual bleeding pattern and its relationship with certain clinical findings in adult women with chd. patients and methods clinical data and menstrual bleeding pattern of adult women ≥15 years old who were referred to adult chd clinic between march and september 2014 were recorded. patients with syndromic congenital anomalies were excluded. results data of 304 w...

introduction patients with palliated congenital heart disease may present later in life for major, non-cardiac surgical procedures. although alternative surgical techniques are now available for the treatment of the transposition of the great arteries (tga), an atrial level baffle (mustard or senning procedure) was previously performed. long-term adverse effects of the atrial level switch inclu...

there is a number of syndromes, associated with proptosis, micrognathia, low-set ear and chest deformity. herein, we report a 9-year-old female with such phenotype who was presented with a vaginal neuroma. the result of karyotype showed 47xx, with extra marker chromosome 22. although such a manifestation had not been reported in the literature, it should be considered as a very rare manifestati...

background: brain type natriuretic peptide (bnp) is a cardiac hormone that is secreted mainly by the ventricles in response to volume expansion and pressure load. it can predict post-operative complications after heart surgery in adults. we sought to investigate the prognostic value of bnp in children after heart surgery. methods: we measured the bnp serum levels in 96 children with congenital ...

background:  levels of anti-inflammatory cytokines in blood have a positive relationship with congenital heart disease (chd). we sought to assess the difference in serum cytokines levels between children with and without chd.  methods:  we recruited 60 patients with chd and 30 healthy children, from 2013 to 2014. patients with primary pulmonary hypertension; metabolic diseases; renal, endocrine...