BACKGROUND The aim of this study was to investigate the relationship between congenital hypothyroidism and several variables using two different adjustment methods. METHODS This matched case-control study was conducted in Hamadan Province, the west of Iran, in 2012 enrolling neonates born between 2005 and 2011 and covered by screening program for congenital hypothyroidism. The neonates with T...

Pendred syndrome is an autosomal recessive disorder characterized by goiter and congenital deafness. The primary defect is not yet known, although the gene causing Pendred syndrome has been localized very recently on chromosome 7q, a region that also contains a gene responsible for nonsyndromal hearing loss (DFNB4). We confirmed linkage to this chromosome 7 region in five Pendred families origi...

BACKGROUND Agenesis of the isthmus associated with nontoxic solitary nodular goiter is a rare congenital anomaly. Imaging data exceptionally has been previously reported in the English language literature. CASE PRESENTATION Preoperative assessment of a 22-year-old white man patient showed an asymptomatic nodule of the thyroid at the left lobe, measuring 2.3 x 1.5 cm in diameter without region...

background: fanconi anemia (fa) is a rare, autosomal recessive (ar) and multifactorial disorder. a high prevalence of fa observed in iran is perhaps due to the high rate of consanguineous marriages. this study investigates the extent of short stature in patients with fa, the frequency of hypothyroidism in fa and the correlation between height and hypothyroidism.   methods: eighteen patients wit...

the objectives of the present study were to investigate the prevalence of histologic thyroids lesions and the respective thyroid hormones changes of ewes in an endemic goiter region and to find out any impact of this condition on the fetal thyroid structures and serum thyroid hormones. in the present study a total number of 100 pregnant ewes and their fetuses slaughtered at slaughterhouse were ...

Background: Fanconi anemia (FA) is a rare, autosomal recessive (AR) and multifactorial disorder. A high prevalence of FA observed in Iran is perhaps due to the high rate of consanguineous marriages. This study investigates the extent of short stature in patients with FA, the frequency of hypothyroidism in FA and the correlation between height and hypothyroidism. Methods: Eighteen patients with ...

The objectives of the present study were to investigate the prevalence of histologic thyroids lesions and the respective thyroid hormones changes of ewes in an endemic goiter region and to find out any impact of this condition on the fetal thyroid structures and serum thyroid hormones. In the present study a total number of 100 pregnant ewes and their fetuses slaughtered at slaughterhouse were...

background: goiter is thyroid enlargement, which is the most common visible symptom of iodine deficiency. some studies have shown iodine deficiency in water, soil, and food in many places worldwide. we aimed to determine the prevalence of goiter and the association between urine iodine levels in children with severity and prevalence of goiter in mountainous villages of kashan city (center of ir...

thyroid tissue located within the upper airway has received only sparse attention in the english literature. aberrant benign thyroid masses may present as either an unrelated autopsy finding or with symptoms such as dyspnea, hemoptysis or adult -onset asthma. there is no place for medical management in the therapy of these lesions, although the appropriate surgical procedure is not clearly esta...