In many biomedical studies, the event of interest can occur more than once in a participant. These events are termed recurrent events. However, the majority of analyses focus only on time to the first event, ignoring the subsequent events. Several statistical models have been proposed for analysing multiple events. In this paper we explore and illustrate several modelling techniques for analysi...

Abstract To achieve the goal of sustainable employment, considering profile Portuguese working population (PWP), is needed a range strategies to ensure long, productive, and careers allied with better quality life, health, wellbeing, but also public health policies grounded on scientifically validated reliable data. This possible through comprehensive system approach that ensures workers will b...

In this paper, a 2-stage cascaded deep learning framework, Port Wave Prediction Network (PWPNet), is proposed for real-time prediction of significant wave height (SWH) distribution in port. The PWP-out model the first stage, predicting port-entrance parameters, utilizes three branches, branch using Long Short Term Memory (LSTM) module to learn temporal dependencies time sequences second and Win...

BACKGROUND Right ventricular (RV) afterload is an important risk factor for post-heart transplantation (HTx) mortality, and it results from the interaction between pulmonary vascular resistance (PVR) and pulmonary compliance (CPA). Their product, the RC time, is believed to be constant. An exception is observed in pulmonary hypertension because of elevated left ventricular (LV) filling pressure...

The influence offrusemide on haemodynamic, electrocardiographic, and symptomatic response to exercise was studied in 19 patients with documented coronary artery disease. During the control exercise period all patients experienced angina and showed ST segment depression, accompanied by raised pulmonary artery wedge pressures (PWP). In 12 of these patients 40 mg frusemide was administered intrave...

Left ventricular function was assessed in 10 patients with alcoholic cirrhosis and ascites without clinical evidence of heart disease. In the resting state pulmonary wedge pressure (PWP) was normal (average 9.7 mm Hg), cardiac output (CO) was elevated (average 9.7 L/min) and systemic vascular resistance (SVR) was low (average 825 dynes-sec-cm-5). During infusion of angiotensin in a dose suffici...

BACKGROUND Evidence for longer term exercise delivery for people with Parkinson's disease (PwP) is deficient. AIM Evaluate safety and adherence to a minimally supported community exercise intervention and estimate effect sizes (ES). METHODS 2-arm parallel phase II randomised controlled trial with blind assessment. PwP able to walk ≥100 m and with no contraindication to exercise were recruit...

The PWP method was introduced by Dı́az in 2009 as a technique for measuring indirect influences in complex networks. It depends on a matrix D, provided by the user, called the matrix of direct influences, and on a positive real parameter λ which is part of the method itself. We study changes in the method’s predictions as D and λ vary.