a facility location is said to be competitive when other facilities are present in the market and new facilities have to compete with these existing facilities for a market share. in other words, in a competitive facility location problem we do not see monopoly that exists in classic location models. in such a situation, existing facilities react to locate new facilities by adjusting their attr...

Mechanism design studies how to design mechanisms that result in good outcomes even when agents strategically report their preferences. In traditional settings, it is assumed that a mechanism can enforce payments to give an incentive for agents to act honestly. In many Internet application domains, however, introducing monetary transfers is impossible or undesirable. Also, in such highly anonym...

Linker DNA was found to be critical for the specific docking of ISW2 with nucleosomes as shown by mapping the physical contacts of ISW2 with nucleosomes at base-pair resolution. Hydroxyl radical footprinting revealed that ISW2 not only extensively interacts with the linker DNA, but also approaches the nucleosome from the side perpendicular to the axis of the DNA superhelix and contacts two disp...

A stochastic search algorithm for local multi-objective optimization is developed and applied to solve a multi-objective competitive facility problem for firm expansion using shared-memory parallel computing systems. The performance of the developed algorithm is experimentally investigated by solving competitive facility location problems, using up to 16 shared-memory processing units. It is sh...

We consider the online variant of facility location, in which demand points arrive one at a time and we must maintain a set of facilities to service these points. We provide a randomized onlineO(1)-competitive algorithm in the case where points arrive in random order. If points are ordered adversarially, we show that no algorithm can be constant-competitive, and provide an O(logn)-competitive a...

This study seeks to explain why, in some cases, locationally advantageous countries attract foreign firms, who develop dominant competitive positions in the market, rather than facilitate the development of internationally competitive national firms, as theory suggests. Comparative analyses of samples of foreign and British-owned insurance firms in the London wholesale insurance market are used...

Competition ChIP is an experimental method that allows transcription factor (TF) chromatin turnover dynamics to be measured across a genome. We develop and apply a physical model of TF-chromatin competitive binding using chemical reaction rate theory and are able to derive the physical half-life or residence time for TATA-binding protein (TBP) across the yeast genome from competition ChIP data....