Cellular signaling involves a cascade of recognition events occurring in a complex environment with high concentrations of proteins, polysaccharides, and other macromolecules. The influence of macromolecular crowders on protein binding affinity through hard-core repulsion is well studied, and possible contributions of protein-crowder soft attraction have been implicated recently. Here we presen...

—The anomaly zone presents a major challenge to the accurate resolution of 1 many parts of the Tree of Life. The anomaly zone is defined by the presence of a gene tree 2 topology that is more probable than the true species tree. This discrepancy can result from 3 consecutive rapid speciation events in the species tree. Similar to the problem of 4 long-branch attraction, including more data (loc...

Concerns about the deleterious effects of missing data may often determine which characters and taxa are included in phylogenetic analyses. For example, researchers may exclude taxa lacking data for some genes or exclude a gene lacking data in some taxa. Yet, there may be very little evidence to support these decisions. In this paper, I review the effects of missing data on phylogenetic analyse...

Competitive accretion occurs when stars in a cluster accrete from a shared reservoir of gas. The competition arises due to the relative attraction of stars as a function of their mass and location in the cluster. The low relative motions of the stars and gas in young, gas dominated clusters results in a tidal limit to the accretion whereas in the stellar dominated cluster cores, the high relati...

Attraction interference in language comprehension and production may be as a result of common or different processes. In the present paper, we investigate attraction interference during language comprehension, focusing on the contexts in which interference arises and the time-course of these effects. Using evidence from event-related brain potentials (ERPs) and sentence judgment times, we show ...

In natural visual experience, different views of an object or face tend to appear in close temporal proximity as an animal manipulates the object or navigates around it, or as a face changes expression or pose. A set of simulations is presented which demonstrate how viewpoint-invariant representations of faces can be developed from visual experience by capturing the temporal relationships among...