Neonatal forelimb amputation in rats produces sprouting of sciatic nerve afferent fibers into the cuneate nucleus (CN) and results in 40% of individual CN neurons expressing both forelimb-stump and hindlimb receptive fields. The forelimb-stump region of primary somatosensory cortex (S-I) of these rats contains neurons in layer IV that express both stump and hindlimb receptive fields. However, t...

Cytogenetically normal acute myeloid leukemia (CN-AML) is the largest and most heterogeneous AML subgroup. It lacks sensitive and specific biomarkers. Emerging evidences have suggested that microRNAs are involved in the pathogenesis of various leukemias. This paper evaluated the association between microRNA expression and prognostic outcome for CN-AML, based on the RNA/microRNA sequencing data ...

Nephrotic syndrome is a glomerular disease commonly seen in paediatric population. The characterized by hypercoagulable state and risk of thromboembolic complications. Cerebral venous thrombosis (CVT) rare complication children associated with nephrotic an incidence 0.67/100000 very few case reports described. 12-year-old girl steroid dependent syndrome- minimal change disease, background recen...

In this paper we study a model quantum register R made of N replicas (cells) of a given finitedimensional quantum system S. Assuming that all cells are coupled with a common environment with equal strength we show that, for N large enough, in the Hilbert space of R there exists a linear subspace CN which is dynamically decoupled from the environment. The states in CN evolve unitarily and are th...

Sleep is a fundamental biological process for all animals. However, the molecular mechanisms that regulate sleep are still poorly understood. Here we report that sleep-like behavior in Drosophila is severely impaired by mutations in sarah (sra), a member of the Regulator of Calcineurin (RCAN) family of genes. Sleep reduction in sra mutants is highly correlated with decreases in Sra protein leve...

Background Diffusion MRI is a valuable tool to assess white matter (WM) microstructure biomarkers of brain aging and Alzheimer’s disease (AD). The most common model used extract diffusion properties the tensor (DTI). However, DTI cannot resolve complex WM suffers from partial volume effects. Further, majority multi-site imaging clinical studies, such as ADNI, are limited single-shell acquisitio...

A set of q triangles sharing a common edge is called a book of size q. We write β (n,m) for the the maximal q such that every graph G (n,m) contains a book of size q. In this note 1) we compute β ( n, cn ) for infinitely many values of c with 1/4 < c < 1/3, 2) we show that if m ≥ (1/4− α)n with 0 < α < 17, and G has no book of size at least ( 1/6 − 2α ) n then G contains an induced bipartite gr...

Genes encoding three putative endopeptidases were identified from a draft-quality genome sequence of Lactobacillus helveticus CNRZ32 and designated pepO3, pepF, and pepE2. The ability of cell extracts from Escherichia coli DH5alpha derivatives expressing CNRZ32 endopeptidases PepE, PepE2, PepF, PepO, PepO2, and PepO3 to hydrolyze the model bitter peptides, beta-casein (beta-CN) (f193-209) and a...