نتایج جستجو برای: comet
تعداد نتایج: 7626 فیلتر نتایج به سال:
We report the first results of a research program to explore the sensitivity of the orbits of Oort cloud comets to changes in the strength of the Galactic tides in the plane of the disk and also to changes in the mass of the host star. We performed 2D simulations that confirm that the effects of the tides on comet orbits are sensitive to a star’s distance from the Galactic center. A comet cloud...
BACKGROUND/AIMS The role of Helicobacter pylori in gastric carcinogenesis is unclear, but H. pylori infection is thought to predispose carriers to gastric cancer. The aim of this study was to investigate the relationship between the extent of DNA damage in normal gastric epithelial cells and H. pylori-positive and -negative gastritis according to histological diagnosis. We also compared the per...
Today’s computers have gigabytes of main memory due to improved DRAM density. As density increases, smaller bit cells become more susceptible to errors. With an increase in error susceptibility, the need for memory resiliency also increases. Self-testing of memory health can proactively check for errors to improve resiliency. This paper describes a software-only self-test to continuously test m...
White spot syndrome virus (WSSV) is the causative agent of a disease which has recently caused high shrimp morbidity, mortality and severe damage to shrimp cultures. In this study a strain of WSSV from tiger shrimp Penaeus monodon was used to detect DNA damage in muscle cells by using Comet Assay. The term "comet" refers to the pattern of DNA migration through the electrophoresis gel, which oft...
The spindle assembly checkpoint links the onset of anaphase to completion of chromosome-microtubule attachment and is mediated by the binding of Mad and Bub proteins to kinetochores of unattached or maloriented chromosomes. Mad2 and BubR1 traffic between kinetochores and the cytosol, thereby transmitting a "wait anaphase" signal to the anaphase-promoting complex. It is generally assumed that th...
In recent years the Comet assay (or single cell gel electrophoresis assay) has been established as a rapid and sensitive method for the detection of DNA damage. For early genotoxicity screening of new chemical entities in industrial toxicology, the Comet assay is more and more used for assessment of the DNA damaging potential of a test compound. In order to increase compound screening throughpu...
Phthalates are industrial chemicals widely used in many commercial applications. The general population is exposed to phthalates through consumer products as well as through diet and medical treatments. To determine whether environmental levels of phthalates are associated with altered DNA integrity in human sperm, we selected a population without identified sources of exposure to phthalates. O...
Introduction: Several studies have shown that DNA damages increase the risk of diseases such as cancer. One of the tests that used to assess the damage to DNA is Comet Assay. In this study, the initial damage caused by exposure to traffic-related air pollution was studied. Methods: In this analytic cross sectional study, 104 taxi drivers were selected in Yazd, Iran. Peripheral blood sampling...
Slight hypercalcemia is not associated with positive responses in the Comet Assay in male rat liver.
Maintenance of physiological levels of intracellular and extracellular calcium is essential for life. Increased intracellular calcium levels are involved in cell death (apoptosis and necrosis) and are associated with positive responses in the Comet assay in vitro. In addition, high calcium and vitamin D intakes were reported to induce apoptosis in adipose tissue in obese mice and to increase DN...
A collaborative trial was conducted to evaluate the possibility of integrating the rat-liver Comet assay into repeat-dose toxicity studies. Fourteen laboratories from Europe, Japan and the USA tested fifteen chemicals. Two chemicals had been previously shown to induce micronuclei in an acute protocol, but were found negative in a 4-week Micronucleus (MN) Assay (benzo[a]pyrene and 1,2-dimethylhy...
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