Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disorder of the small intestine colon. IBD includes ulcerative colitis (UC) Crohn’s (CD), it main reason for expansion colon cancer, referred to as colitis-associated cancer (CAC). Oral colon-targeted microsphere based drug delivery system containing sulfasalazine was prepared, optimized characterized. The micros...

background: to determine the colon transit time (ctt) in patients complaining of functional constipation and to evaluate the correlation between abnormal transit times and the types of constipation and the correlation with age and sex. materials and methods: the signs and symptoms of 84 patients with infrequent or difficult defecation, 33 males and 51 females, with a median age of 33.7 were rec...

Introduction Dose calculation of tumor and surrounding tissues is essential during prostate brachytherapy. Three radioisotopes, namely, 125I, 103Pd, and 131Cs, are extensively used in this method. In this study, we aimed to calculate the received doses by the prostate and critical organs using the aforementioned radioactive seeds and to investigate the effect of scattering contribution for the ...

background: there are many preparation regimens for bowel cleansing. given their adverse effects, none of them have been considered perfect by the endoscopists. the aim of this study was to compare the effects of two bowel cleansing regimens on clean colonic preparation the subjects'well being and electrolyte balance. materials andmethods: atotal number of 280 patients were randomly assigned to...

in western countries there is a growing incidence in obesity, inflammatory bowel disease (ibd) and colorectal cancer (crc), which places an increasingly important burden on the health care system. in the current decade, changes in intestinal microflora (i.e., dysbiosis) are likely the result of environment factors such as food, lifestyle, and medications which have been shown in obesity and ibd...

conclusions due to the significant reduction in the mean inactivation dose of colon cancer cells in the presence of gold nanoparticles, it seems that gnps are suitable options to achieve a new approach in order to improve radiotherapy efficiency without increasing the prescribed radiation dose. results cell survival in the presence of gnps was more than 90% and the maximum uptake of gnps was ob...

most patients with gastrointestinal cancers refer to the health centers at advanced stages of the disease and conventional treatments are not significantly effective for these patients. therefore, using modern therapeutic approaches with lower toxicity bring higher chance for successful treatment and reduced adverse effects in such patients. the aim of this study is to evaluate the effect of av...

b a c k g r o u n d  & aim: it is very helpful to classify and predict the clinical  category  of a sample based  on  its  gene  expression  profile.  this  study  was  conducted  to predict  tissues  of colorectal adenoma,  adenocarcinoma,  and  paired  normal  in  colon  based  on  microarray  data  using  nearest shrunken centroid method. methods   &  materials:    in  this  study,   the  co...

background: arteriovenous malformations are one of the most common vascular disorders of the colon. vascular disorders present as painless, high-volume rectal bleeding. case presentation: this study elucidates two rare cases of vascular disorders that are diagnosed as angiodysplasia of the left colon and cavernous hemangioma of the colon and rectum.  the chief complaint in two patients was rect...