Prenatal cold stress is one of the earliest factors affecting mammalian health, and is associated with neonatal growth retardation and immune dysfunction, thus increasing disease susceptibility. The mechanisms underlying these observations remain unclear; hence, the objective of this study was to elucidate placental responses to cold stress. 60 maternal rats were randomly allocated to either st...

Antioxidant and pro-oxidant systems were studied in overwintering larvae of two cold-hardy gall insect species, the freeze-tolerant fly Eurosta solidaginis and the freeze-avoiding moth Epiblema scudderiana. An increase in the levels of the oxidized form of glutathione suggested slight oxidative stress in both species during the winter. Freeze-tolerant Eurosta solidaginis larvae generally had de...

Exposure of the skin to UVB radiation causes skin damage. UVB is considered lethal as it spontaneously causes sunburn, is genotoxic, and responsible for significant depletion of dermal antioxidants (enzymic and non-enzymic). It initiates photochemical reactions resulting in extensive free radical generation and in turn oxidative stress. The harmful effects of chemical based commercial sunscreen...

background: this study investigated the protective effects of aqueous extracts of anogeissus leiocarpus (dc) guill & perr (combretaceae) and terminalia avicennioides guill & perr (combretaceae) root barks, as well as their 1:1 (w/w) mixture on liver redox and haematological parameters of diethylnitrosamine-treated rats. methods: rats were orally administered distilled water, diethylnitrosamine ...

background: diabetes is one of the most common metabolic disorders and is related to oxidative-stress-induced diseases. given the role of dietary antioxidants in the control and prevention of diabetes, this study aimed to examine the effects of sesame butter versus sesame oil on the serum levels of glucose, lipid profile, and oxidative stress biomarkers in diabetic rats. methods: forty male alb...

conclusions despite the presence of vast oxidative stress in hepatitis b, antioxidant therapy is not always effective as a treatment strategy, especially considering that antioxidants can act as “double-edged swords” or antioxidants; if not used at the right time or place or in the right combination, these substances can easily become pro-oxidants. therefore, several studies will be needed to d...