نتایج جستجو برای: codon optimized

تعداد نتایج: 112368  

2016
Donald R. Forsdyke

While confirming the long held view that “viruses do not closely imitate the use of the [host’s] ... codon catalogue” (Grantham et al., 1986), it is nevertheless considered a “surprising finding” that “despite having the ability to infect the same host, many mycobacteriophages share little or no genetic similarity” (i.e. similarity in their “GC contents and codon utilization patterns;” Esposito...

Journal: :Journal of virology 2015
Priya Bellare Andrew Dufresne Don Ganem

UNLABELLED Latent Kaposi's sarcoma-associated herpesvirus (KSHV) genomes encode a homolog of cellular FLICE-inhibitory proteins (termed v-FLIP) that activates NF-κB and can trigger important proinflammatory and antiapoptotic changes in latently infected cells. The protein is present at very low levels in infection and has generally been difficult to efficiently express in recombinant vectors. H...

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