Due to the inaccessibility of the inner ear, direct in vivo information on cochlear mechanics is difficult to obtain. Mathematical modelling is a promising way to provide insight into the physiology and pathology of the cochlea. Finite element method (FEM) is one of the most popular discrete mathematical modelling techniques, mainly used in engineering that has been increasingly used to model t...

Conservation of a patient's residual hearing and prevention of fibrous tissue/new bone formation around an electrode array are some of the major challenges in cochlear implant (CI) surgery. Although it is well-known that fibrotic tissue formation around the electrode array can interfere with hearing performance in implanted patients, and that associated intracochlear inflammation can initiate l...

A digital cochlea, which has a cascade of 16 filter sections, is realized by 32 commercially available DSP-boards. Each section consists of travelling waves filter, velocity transformation filter and second filter. The artificial cochlea is also applied to spoken word recognition by feeding 16 output signals through a multi-channel A/D converter on PC From experimental results, it is found that...

The endolymphatic potential was recorded from various vestibular parts of the labyrinth from which the cochlea (in the case of guinea pigs) or the cochlea, lagena, and sacculus (in the case of pigeons) had been removed. This endovestibular potential of the isolated vestibule declined during anoxia and recovered after anoxia in the same manner as the endovestibular potential of the intact labyri...

Sound transduction within the auditory portion of the inner ear, the cochlea, is a complex nonlinear process. The study of cochlear mechanics in large rodents has provided important insights into cochlear function. However, technological and experimental limitations have restricted studies in mice due to their smaller cochlea. These challenges are important to overcome because of the wide varie...

Cochlear implants are electronic devices that are used to restore hearing to individuals with severe-toprofound sensorineural loss via direct stimulation of the auditory nerve. Implantation requires the insertion of an electrode into human cochlea. This project aims at developing a safe robotic approach for minimizing intracochlear trauma during electrode insertion and consequently preserving t...

This paper presents an electronic system that extracts the periodicity of a sound. It uses three analogue VLSI building blocks: a silicon cochlea, two inner-hair-cell circuits and two spiking neuron chips. The silicon cochlea consists of a cascade of filters. Because of the delay between two outputs from the silicon cochlea, spike trains created at these outputs are synchronous only for a narro...

Automatic detection of abnormal anatomies or malformations different structures the human body is a challenging task that could provide support for clinicians in their daily practice. Compared to normative anatomies, there low presence anatomical abnormalities patients, and great variation within make it design deep learning frameworks automatic detection. We propose framework abnormality detec...

Topological distributions of individual cellular clocks have not been demonstrated in peripheral organs. The cochlea displays circadian patterns of core clock gene expression [1, 2]. PER2 protein is expressed in the hair cells and spiral ganglion neurons of the cochlea in the spiral ganglion neurons [1]. To investigate the topological organization of cellular oscillators in the cochlea, we reco...

The coiled cochlea is a key evolutionary innovation of modern therian mammals. We report that the Late Jurassic mammal Dryolestes, a relative to modern therians, has derived bony characteristics of therian-like innervation, but its uncoiled cochlear canal is less derived than the coiled cochlea of modern therians. This suggests a therian-like innervation evolved before the fully coiled cochlea ...