Abstract Post-operative meningitis is a rare but potentially fatal complication of endoscopic endonasal skull base surgery. As approaches to the are clean-contaminated procedures, peri-operative antibiotics routinely used. We sought analyse safety and efficacy single agent, dose protocol in cases anterior Database all skull-base procedures performed ENT Department at Leeds General Infirmary bet...

OBJECTIVES The objectives of this study were to determine antimicrobial resistance and to identify phage types and class 1 integrons among non-typhoidal Salmonella isolates from 24 pig farms in North Carolina collected between 1997 and 2000. METHODS A total of 1314 isolates of 30 serotypes from pig faecal samples were collected and analysed over a 3 year period. The isolates were characterize...

OBJECTIVES To compare the antimicrobial susceptibility of Prevotella spp. isolated from cystic fibrosis (CF) and non-CF patients and analyse the impact of antibiotic prescribing in the preceding year on resistance amongst CF isolates. METHODS The susceptibility of 80 CF Prevotella isolates to 12 antibiotics was compared with that of 50 Prevotella isolates from invasive infections in people wh...

Adverse events and laboratory abnormalities were monitored over 35 days after the commencement of treatment in 45 open studies conducted in Europe, South America, Africa and Asia. These studies were to assess the clinical efficacies of azithromycin and comparator antimicrobial agents in the treatment of paediatric acute bacterial infections. Children (6 months-16 years of age) had been treated ...

Insusceptibility levels of cefaclor and other commonly prescribed antibiotics were determined for 489 consecutive hospital and community-associated urinary tract isolates of Escherichia coli from the Nottingham area of the UK. Significant resistance (MIC of > or = 8 mg/L) to cefaclor was found to be uncommon in the UK, with insusceptibility percentages as low as 1.5% and 1.4% amongst hospital a...

OBJECTIVES We tested a previously published model for the analysis of the temporal relationship between antibiotic use and the incidence of Clostridium difficile infection in a hospital with stable incidence of infection at >1 case per 1000 admissions per month. METHODS The study period was from April 2004 to June 2008 and used data from Infection Control and Hospital Pharmacy. We first descr...

OBJECTIVES The aim of this study was to investigate antimicrobial prescribing in nursing homes in countries across Europe. METHODS Point prevalence studies were completed in April and November 2009 in 85 nursing homes in 15 European countries and two UK administrations. RESULTS A total of 10,388 and 9430 residents participated in April and November 2009, respectively. The mean prevalence of...

objective this research was carried out to compare antibacterial effect of rosa nutkana sepal extract with synthetic antibiotics on methicillin resistant staphylococcus aureus (mrsa) bacteria isolated from patients with sty. patients and methods this descriptive study was done in 2009 at remedial center of shahid beheshti university and sampling was performed from patients suffering from sty us...