OBJECTIVE Cytomegalovirus (CMV), a ubiquitous virus belonging to the herpes family, is known to be transmitted frequently to developing fetuses in pregnancy. In an immunocompromised state like pregnancy, primary infection through blood transfusion or reactivation of a latent CMV infection can cause severe illness. The study was carried out to determine the seroprevalence of the immunoglobulin G...

Three hundred and forty serum samples collected from women of child bearing age, without any clinical evidence of cytomegalovirus (CMV) infection, were screened for the presence of IgG antibodies against CMV by ELISA test. The IgG antibodies were detected in 297 which gave prevalence rate of 87.4%. Significantly higher prevalence rates (p < 0.001) were observed with increasing age and with incr...

BACKGROUND Cytomegalovirus (CMV) is the most common cause of congenital infection, with increased morbidity and mortality at birth. The risk of intrauterine infection largely depends on the time of maternal infection during pregnancy. Currently, no national screening test for CMV infection is available during pregnancy in Iran. The aim of this study was to determine the seroprevalence of CMV in...

OBJECTIVES Human cytomegalovirus (CMV), a double-strand DNA herpesvirus, can be transmitted via blood transfusion which is especially important for immunocompromised recipients and can cause a fatal infection. CMV seroprevalence in Iran was studied on blood donors, healthy subjects, and some patients. Highly variable rates were detected. The purpose of this study was to review CMV seroprevalenc...

Human cytomegalovirus (CMV) is one of the eight viruses belonging to the Herpesviridae family to infect humans. CMV belongs to the Betaherpesvirinae subfamily of viruses characterized by a restricted host spectrum, in vitro replication in fibroblasts of the natural host species in vivo, a slow replication cycle, the induction of intranuclear and intracytoplasmic inclusions and the ability to in...

In this study, we investigated the prevalence of antibodies against 9 viral species found in umbilical cord blood from 561 neonates in 2013. Serum IgG antibodies against the following viruses were measured: herpes simplex virus (HSV), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), human herpesvirus 6 (HHV-6), measles virus (MV), rubella virus (RV), mumps virus (M...

Cytomegalovirus (CMV) is a major cause of congenital infection in humans. Most of the congenitally infected infants (85%-90%) are asymptomatic at birth but 5% to 15% of them develop sequelae mostly as sensorineural hearing loss, visual impairment or delay of psychomotor development. The prevalence of congenital infection ranges from 0.3% to 2.3% of all live births in different populations[1]. I...

BACKGROUND Since African-Americans have twice the prevalence of cytomegalovirus (CMV) infections as age-matched Caucasians we sought to determine the ages and possible sources of infection of African-American children. METHODS Subjects were 157 African-American healthy children and adolescents and their 113 household adults in Richmond VA. Families completed a questionnaire, provided saliva f...

In Africa, human cytomegalovirus (CMV) is an important pathogen in a diverse range of patient groups. Congenital CMV infection is common, and most children undergo primary infection during the first year of life. Preliminary studies suggest that these early primary CMV infections could have population-wide effects on growth and development. In most studies of adults, CMV seroprevalence is close...

Bate et al [1] present stimulating work on the seroprevalence of cytomegalovirus (CMV) in the United States during 2 periods, 1988–1994 and 1999–2004, which showed that the prevalence of CMV infection remained stable between these 2 periods. Such studies are rare, and many countries clearly lack epidemiologic data. The past decade has seen numerous studies of the management and consequences of ...