The prevalence of cytomegalovirus (CMV) in HIV infected patients is 90%. Both CMV and HIV are involved in the pathogenesis of metabolic and cardiovascular diseases. The study retrospectively evaluated the correlation of CMV infection with lipodystrophy (LD) and hypertension (HTA) in HIV patients who have been beneficiaries of medical care in Galați, during 2013. The evolution of anthropometric ...

This case-control study investigated whether previous infection with cytomegalovirus (CMV) was associated with coronary heart disease (CHD). In total, 312 patients of German nationality aged 40-68 years who had a coronary stenosis of >50% of the luminal diameter were recruited for study. Controls (n=479) were voluntary blood donors. CMV serology was performed to determine presence of specific C...

Background and Aims: Cytomegalovirus (CMV) has worldwide distribution, and its prevalence rate depends on factors such as economic and geographical conditions. An important way of the virus transmission is via blood. Due to high prevalence of anti-CMV antibodies in blood donors and lack of data concerning its seroprevalence in the region, this study was carried out to determine the prevalence r...

Maternal antibodies may protect the fetus and neonate against severe forms of CMV-caused disease, therefore this study investigated the efficiency of the placental transfer of naturally acquired, maternal total anti-cytomegalovirus (CMV) IgG and neutralizing antibodies at different gestational ages. The study was conducted on 182 healthy CMV-seropositive Brazilian mothers and their 196 infants ...

BACKGROUND Measures to prevent transfusion-transmitted cytomegalovirus (TT-CMV) infection after hematopoietic stem cell transplantation (HSCT) include transfusion of CMV antibody-negative blood units and/or transfusion of leukoreduced cellular blood products. We assessed the incidence of TT-CMV in CMV-seronegative patients receiving CMV-seronegative HSC transplants, who were transfused with leu...

Previous studies have documented discordant cellular and humoral immune responses to subjects exposed to HIV-1, and that the nature of such responses may determine susceptibility and resistance to disease. We determined whether there is a spectrum of cellular versus humoral immunodominant responses to cytomegalovirus (CMV) infection. Blood samples from 50 healthy blood donors were tested for an...

OBJECTIVES Immune response to cytomegalovirus (CMV) impacts adult chronic disease. This study investigates associations of childhood and adulthood social environment, socioeconomic position (SEP) and social mobility with CMV response in young adults. DESIGN Historical prospective study design. SETTING Subcohort of all 17 003 births to residents of Jerusalem between 1974 and 1976. PARTICIP...