background and purpose: candidiasis is a major fungal infection, and candida albicans is the major cause of infections in humans. the clinical and laboratory standards institute (clsi) developed new breakpoints for antifungal agents against c. albicans. in this multi-center study, we aimed to determine the drug susceptibility profile of c. albicans, isolated from iranian population according to...

background: coagulase negative staphylococci (cons) are one of the most common bacteria found on human skin and on mucous membranes as a component of normal flora. the presence of cons in clinical specimens is frequently associated with an infectious aetiology or contamination. objectives: we aimed to evaluate cons species distribution and susceptibility patterns in specimens obtained from clin...

background: this study was performed to determine antifungal activity of silver nanoparticles (nano-ag) compared to voriconazole on clinical and standard strains of aspergillus fumigatus. materials and methods: inhibitory potency of nano-ag was determined using microtiter broth dilution method. susceptibility tests were performed against a. fumigatus isolated from bal (bronchoalveolar lavage) o...

conclusion prevalence of p. aeruginosa producing esbl and mdr strains from our clinical samples and environment is still low. results the highest resistance rates from the isolated p. aeruginosa were shown against piperacillin, imipenem, cefotaxime, ceftriaxone, gentamicin, ceftazidime, aztreonam, and ciprofloxacin, respectively. seven isolates (9.2%) were esbl producers. more than 30% of the i...

background & objectives:staphylococcus aureus is one of the major causes of nosocomial infections. recently, increase in its various drug-resistant strains, has increased health problems. incidence of vrsa (vancomycin resistant staphylococcus aureus) strains has created many concerns about the treatment of these bacterial infections. the aim of this study was to determine the frequency of staph...

background: staphylococcus aureus is a major human pathogen. due to high prevalence of s. aureus infections and increasing resistance to antibiotics, physicians have been facing problems in choosing the appropriate empirical antibiotic therapy for such infections. objectives: the aim of this study was to determine the pattern of antibiotic resistance in s. aureus clinical isolates of mashhad qu...