conclusions the results revealed that the novel multi-epitope dna construct could be an effective candidate in tuberculosis vaccine development, and it is qualified to investigate its potential to induce cd4 and cd8 t- cell immune response in the experimental animal model. results mhc class i-and class ii-predicted epitopes showed a high potential to binding to human hlas alleles, with global b...

background & aim: repair or replacement of restorations is one of the main necessities for health promotion. however, it has its own physical, psychological and economical side effects. the aim of this study was to investigate the prevalence of factors causing restoration replacement or repair. methods & materials: a non probable sampling was used for this cross – sectional observational descri...

ulcerative colitis (uc) is a nonspecific acute and chronic inflammatory bowel disease that diffusely involves the colonic mucosa. the etiology of uc has not yet been elucidated fully. however, many studies have found that immunologic disorders may play a role in the pathogenesis of uc. in addition, due to an increased frequency of uc in families, especially an increased monozygotic compared wit...

background and aims: the indiscriminate use of antibiotics can lead to antibiotic resistance in the treatment of infections caused by bacteria such as pseudomonas aeruginosa. the presence of integrons in pseudomonas is clearly associated with multidrug resistances. therefore, this study aimed at tracking class i, ii and iii integrons of antibiotic-resistant isolates of pseudomonas aeruginosa th...

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background: non-hodgkin lymphoma (nhl) includes a wide range of diseases with different clinical and biological features. nhl is usually presented as localized or generalized lymphadenopathy. it has been suggested that the hla class i and ii are associated with susceptibility to nhl. different ethnic groups have been found to have different hla class i and ii alleles which affect nhl. objective...