Laboratory tests (March 4) revealed hemoglobin 11.3 g/ dl, hematocrit 35%, mean corpuscular volume 85 fL, platelet 281,000/mm3, leukocytes 14,400/mm (neutrophils 81%, eosinophils 1%, lymphocytes 11% and monocytes 7%), creatinine 0.93 mg/dl, urea 42 mg/dl, sodium 145 mEq/l, potassium 3.4 mEq/l, C-reactive Protein 172 mg/l, troponin I < 0.20 ng/ml, CKMB 2,17 ng/ml, prothrombin time (INR) 1.2 and ...

Reported proportionsofcreatine kinase (CK; EC 2.7.3.2) MB isoenzyme (CK-MB) in skeletal muscles range from 0 to 28% (1-6). Recent observations of increased activities of CKMB in marathon runners have renewed the interest in studying the proportions of CK isoenzymes in skeletal muscle (7-9). Because previous studieswere limited to a few locations and a few types of muscles, we have carried out a...

Analytical interference in laboratory assays is not only unpredictable but also an underestimated problem. Not recognising these interferences can lead to misdiagnosis and mismanagement of patients. We present a case of a patient with chest pain and ischaemic risk factors with incongruent biochemical results. These results were discovered to be due to the presence of macro-creatine kinase (macr...

OBJECTIVE To observe the effect of methylprednisolone (MP) plus adrenaline to treat patients injured by wasp stings. METHODS This study was carried out at The First College of Clinical Medical Science, China Three Gorges University, Yichang, Hubei Province, China, from June to November 2008. A total of 45 cases were divided into 2 groups. The MP was used alone in the control group, and MP plu...

OBJECTIVES To compare cardiac troponin T, myoglobin, CK, CKMB activity, CKMB mass and the initial electrocardiogram in the early diagnosis of myocardial infarction in the emergency department. Methods-Biochemical markers were measured at presentation in patients with a possible diagnosis of acute myocardial infarction. Based on the clinical notes, patients were grouped as "definite myocardial i...

BACKGROUND Recent studies have proposed a unified genetic model for Facioscapulohumeral muscular dystrophy (FSHD), identifying potential therapeutic targets for future clinical trials. Serum biomarkers related to disease activity will be important for proof of concept or early phase clinical studies. OBJECTIVE To identify potential serum biomarkers in FSHD for possible use in future clinical ...

This study investigated the effects of three sport-specific high-intensity training units on cardiac biomarker alteration in elite athletes of dragon boating. Thirty six male (age 33 ± 9) and twenty nine female (age 31 ± 8) elite athletes, members of the German national team, were examined in their final training camp preparing for world championship. At two time points blood panels (pre-traini...

We investigated the net myocardial release of creatine kinase isoenzyme MB (CKMB), myoglobin, cardiac troponin T (cTnT), cardiac troponin I (cTnI), and cardiac beta-type myosin heavy chain (beta-MHC) into the coronary circulation after cardioplegic cardiac arrest in humans. Cardiac markers were measured in paired arterial, central venous, and coronary sinus blood in 19 patients undergoing elect...