Bag of Marbles (Bam) is known to function as a positive regulator of hematopoietic progenitor maintenance in the lymph gland blood cell-forming organ during Drosophila hematopoiesis. Here, we demonstrate a key function for Bam in cells of the lymph gland posterior signaling center (PSC), a cellular domain proven to function as a hematopoietic niche. Bam is expressed in PSC cells, and gene loss-...

BACKGROUND To examine factors predicting type of bladder antimuscarinics (BAM) initiated in nursing home (NH) residents. METHODS Incident BAM initiators following NH admission were identified by constructing a retrospective cohort from Medicare files and Minimum Data Set (MDS). Participants included all residents 65 years and older admitted in Medicare-certified NH between January 1, 2007 and...

The Rsamtools package provides an interface to BAM files. BAM files are produced by samtools and other software, and represent a flexible format for storing ‘short’ reads aligned to reference genomes. BAM files typically contain sequence and base qualities, and alignment coordinates and quality measures. BAM files are appealing for several reasons. The format is flexible enough to represent rea...

2,6-Dichlorobenzamide (BAM), a persistent metabolite from the herbicide 2,6-dichlorobenzonitrile (dichlobenil), is the pesticide residue most frequently detected in Danish groundwater. A BAM-mineralizing bacterial community was enriched from dichlobenil-treated soil sampled from the courtyard of a former plant nursery. A BAM-mineralizing bacterium (designated strain MSH1) was cultivated and ide...

The precise mechanisms regulating T-helper function have been intensively investigated. We and others have recently identified a new T-cell-B-cell-activating molecule called T-BAM that directs B-cell differentiation by interacting with the CD40 molecule on B cells. Using a specific monoclonal antibody against T-BAM (5C8), we have previously shown that T-BAM expressing T cells are predominantly ...

Bandwidth Allocation Models (BAMs) configure and handle resource allocation (bandwidth, LSPs, fibre) in networks in general (IP/MPLS/DS-TE, optical domain, other). BAMs currently available for IP/MPLS/DS-TE networks (MAM, RDM, G-RDM and AllocTC-Sharing) basically define resource restrictions (bandwidth) by “class” (traffic class, application ś class, user ś class or other grouping criteria) and...

Cell differentiation commonly dictates a change in the cell cycle of mitotic daughters. Previous investigations have suggested that the Drosophila bag of marbles (bam) gene is required for the differentiation of germline stem cell daughters (cystoblasts) from the mother stem cells, perhaps by altering the cell cycle. In this paper, we report the preparation of antibodies to the Bam protein and ...

Business Activity Monitoring (BAM) the term that Gartner, Inc. introduced to define systems that provide real-time access to critical business performance indicators in order to improve the speed and effectiveness of business operations. Despite the emphasis of BAM on the provision of low-latency views on enterprise performance, the literature on BAM also indicates the technical feasibility of ...

Plant BZR1-BAM transcription factors contain a β-amylase (BAM)-like domain, characteristic of proteins involved in starch breakdown. The enzyme-derived domains appear to be noncatalytic, but they determine the function of the two Arabidopsis thaliana BZR1-BAM isoforms (BAM7 and BAM8) during transcriptional initiation. Removal or swapping of the BAM domains demonstrates that the BAM7 BAM domain ...

Identifying factors that regulate the balance between stem cell self-renewal and differentiation into specialized cells is key to understanding tissue homeostasis and regeneration. Long before the identification of the four factors sufficient to define stemness, a single gene named bag of marbles (bam) was shown to be necessary and sufficient to control the transition from stem cell to differen...