Objectives:Citrobacter spp. especially Citrobacter freundii, is frequently causing nosocomial infections, and increasingly becoming multi-drug resistant (MDR). In this study, we aimed to determine the genetic diversity and relationships of Citrobacter spp. from diarrheal patients and food sources, their antimicrobial resistance profiles and in vitro virulence properties. Methods: Sixty two Citr...

An antigenic scheme, based on the determination of 17 somatic and 9 flagellar antigens, is proposed for Citrobacter koseri. Seven of the flagellar antigens constituted the specific phase (a through g), and the others (1 and 2) were nonspecific. Of the 238 theoretically possible serotypes, 48 were identified among 680 cultures examined.

We purified and sequenced the heat-stable enterotoxin produced by Citrobacter freundii. The toxin was detected during purification by reaction with monoclonal antibody to Escherichia coli heat-stable enterotoxin. The C. freundii toxin amino acid sequence was identical to that of the 18-amino-acid heat-stable enterotoxin (STa) produced by toxigenic E. coli.

heavy metal pollution all around the world has become a major environmental concern and the bioremediation of polluted environments is an increasingly popular strategy due to both its efficiency and safety. in this study, a bacterial strain resistant to heavy metal was isolated from metal contaminated sites. strain mkh2 was removed pb (ii) with 95.06%. this isolate was also resistant to zinc, c...

Citrobacter, a Gram-negative enteric bacillus, is a rare cause of septicemia and meningitis, seldom reported beyond the neonatal period. It is characterized by a fulminant clinical course and a high incidence of complications, including brain abscesses. We studied a three-month-old infant with Citrobacter meningitis, who developed acute communicating hydrocephalus and multiple periventricular b...

Characteristics and antibiotic sensitivities of Citrobacter diversus are described, and a minimal number of diagnostic tests to identify this organism in a clinical laboratory are suggested.

The activity of azlocillin and mezlocillin, new semisynthetic ureido penicillins, was investigated and compared with that of other known beta-lactam antibiotics. At a concentration of 25 mug/ml, azlocillin inhibited 74% of Enterobacter, 97% of Proteus mirabilis, 64% of Citrobacter, 91% of Pseudomonas aeruginosa, and 82% of Bacteroides strains tested. Mezlocillin inhibited 86% of Shigella, 96% o...

Meningitis caused by gram-negative enteric bacteria usually is limited in children to the neonatal period. Among neonates, the disease is severe, with a mortality of up to 80%. The most common etiologic agent in this type of meningitis is Escherichia coli. Meningitis due to Citrobacter diversus has occurred in sporadic small outbreaks throughout the United States. This devastating disease frequ...