* This work was done under contract N7-onr 434 Task Order III, Naval Department, Office of Naval Research. 1 Cartan, H., "Algebraic Topology," Harvard Univ., 1949; Wallace, A. D. "Outline for Algebraic Topology I," Tulane Univ., 1949-1950; and Wallace A. D., "Map Excision Theorem," Duke Math. J., 19 (1952). 2 Cf. Tukey, J. W., "Convergence and Uniformity in General Topology," Ann. Math. Studies...

BACKGROUND Gait impairment is common in parkinsonian syndromes but not specific to striatonigral dysfunction. The relationship between the dopaminergic system and gait parameters is poorly understood. This cross-sectional study aimed to determine if gait measures are related to the striatal dopamine transporters distribution using [(123)I]FP-CIT SPECT in patients with parkinsonian syndromes. ...

Psychophysiological detection of deception has seen increased attention in both research and applied settings. In this field, the most scientifically validated paradigm is the Concealed Information Test (CIT). The CIT does not directly deal with whether a participant is lying, but examines whether a participant recognizes a critical relevant detail, inferred by differences in physiological resp...

ibid., 32. Apparently, this "prophecy" was printed as a poster and displayed in towns in various palts oUndia, which, and this is said to have, "created great consternation" and even forced a discussion on thematter in the British Parliament (Nazirullah, ap. cit., 14). 118. Nazirullah,ap. cit., 15. 119. Deendar Anjuman Ajmali Ta'aruf,ap. cit., 17. J 120. ibid, 20. 121. Nazirullah, ap. cit., 11....

We previously showed that developmental 3,4-methylenedioxymethamphetamine (MDMA) treatment induces long-term spatial and egocentric learning and memory deficits and serotonin (5-HT) reductions. During brain development, 5-HT is a neurotrophic factor influencing neurogenesis, synaptogenesis, migration, and target field organization. MDMA (10 mg/kg × 4/d at 2 h intervals) given on post-natal day ...

Age-related differences in cognitive processes were used to understand agerelated declines in creativity. According to the Geneplore model (Finke, Ward, & Smith, 1992), there are two phases of creativity — generating an idea and exploring the implications of the idea — each with different underlying cognitive processes. These two phases are measured in the Creative Invention Task (CIT; Finke, 1...

Mycotoxins produced by fungal species commonly contaminate livestock feedstuffs, jeopardizing their health and diminishing production. Citrinin (CIT) and ochratoxin A (OTA) are mycotoxins produced by Penicillium spp. and commonly co-occur. Both CIT and OTA can modulate immune response by inhibiting cell proliferation and differentiation, altering cell metabolism, and triggering programmed cell ...

Objectives: To examine the validity of [I]β-CIT SPECT for monitoring the progression of dopaminergic degeneration in Parkinson’s disease; to investigate the influence of short term treatment with D2 receptor agonists on striatal [I]β-CIT binding; and to determine the sample size and frequency of SPECT imaging required to demonstrate a significant effect of a putative neuroprotective agent. Meth...

Objective. To investigate whether citrullinated proteins within the atherosclerotic plaque can be targeted by anti–citrullinated protein antibodies (ACPAs), forming stimulatory immune complexes that propagate the progression of atherosclerosis. Methods. Protein lysates prepared from atherosclerotic segments of human aorta were assessed for the presence of citrulline-modified proteins, and speci...

The synthesis, structure and magnetic properties of a 3D network based on {Co₄(cit)₄}⁸⁻ (H₄cit = citric acid) cubane units linked by octahedral Co(II) centres is reported.