Human and bovine serum albumin (38-377 p ~ ) bound approximately 1 mol of platinum per mol of protein when incubated with 300 t o 600 PM cis-dichlorodiammineplatinum (11) (cis-DDP) for 6 h at 37 “C. Significantly increased binding was not demonstrated with higher concentrations of cis-DDP or longer incubation periods. Bovine albumin that was carboxamidomethylated retained 0.03-0.06 mol of sulfh...

The reaction of [RuCl2(CO)3]2 and Te2Tpn2 (Tpn=thiophen-2-yl, C4H3S) in the absence light resulted formation cct-[RuCl2(CO)2(TeTpn2)2] (1) [cis(Cl)-cis(CO)-trans(TeTpn2)] TeTpn2 (2) together with precipitation tellurium. complex 1 monotelluride 2 were characterized by NMR spectroscopy single-crystal X-ray diffraction. decomposition to has been monitored 125Te seemed be faster than ligand substi...

A comparative study of the spectral-luminescent and spectral-kinetic properties 3,3'-diethyl-9-methylthiacarbocyanine (MTCC) 3,3'-diethylthiacarbocyanine (TCC) their complexes with cucurbit[8]uril in aqueous solution was carried out. Dimeric TCC consist trans-isomers exhibit only delayed fluorescence while dimeric MTCC cis-isomers both phosphorescence water. The participate electron phototransf...

The homotypic fusion of yeast vacuoles requires Sec18p (NSF)-driven priming to allow vacuole docking, but the mechanism that links priming and docking is unknown. We find that a large multisubunit protein called the Vam2/6p complex is bound to cis-paired SNAP receptors (SNAREs) on isolated vacuoles. This association of the Vam2/6p complex with the cis-SNARE complex is disrupted during priming. ...

Objective(s): The present study aims to evaluate the protective effect of the compounds isolated from Echinophora cinerea (E. cinerea) against oxidative stress and apoptosis induced by cisplatin (CIS) in PC12 cells. Materials and Methods: Six compounds were isolated as quercetrin-3-O-β-D-glucopyranoside (QUE), osthol (OST), verbenone-5-O-β-D-glycopyranoside (VER), Isoimperatorin (ISO), kaempfer...

UNLABELLED The Picornaviridae is a large family of positive-sense RNA viruses that contains numerous human and animal pathogens, including foot-and-mouth disease virus (FMDV). The picornavirus replication complex comprises a coordinated network of protein-protein and protein-RNA interactions involving multiple viral and host-cellular factors. Many of the proteins within the complex possess mult...

The regeneration of 11-cis-retinal, the universal chromophore of the vertebrate retina, is a complex process involving photoreceptors and adjacent retinal pigment epithelial cells (RPE). 11-cis-Retinal is coupled to opsins in both rod and cone photoreceptor cells and is photoisomerized to all-trans-retinal by light. Here, we show that RPE microsomes can catalyze the reverse isomerization of 11-...

The present work concerns with an investigation on the solubility of cis,cis-muconic acid dissolution in different polar solvents by characterizing and modeling the dissolution as a function of temperature. Water, ethanol, 2-propanol and acetic acid have been investigated as solvents in the range temperatures from a 298.15 to 348.15 K. Owing to the absence of cis,cis-muconic acid solubility...