A nterior segment optical coherence tomography (OCT) is a noninvasive, painless, noncontact technique that provides accurate and reproducible images. This technique correlates well with ultrasound biomicroscopy, allows observation of iridocorneal angle abnormalities in the presence of opaque media, and is easier to perform than ultrasound biomicroscopy. A cyclodialysis cleft results from separa...

AIMS To determine the long term visual outcome of patients who were eligible for randomisation to enucleation versus brachytherapy in a US collaborative ocular melanoma study (COMS) but were treated with either helium ion or 125I radioactive plaque therapy. METHOD A retrospective analysis was performed of 426 ciliochoroidal melanomas that met COMS inclusion criteria for randomisation to enucl...

OBJECTIVE To investigate the early postoperative complications in two different tube ligation methods during the first 3 months in Baerveldt implant surgery. PARTICIPANTS This study involved 157 eyes from 144 patients who underwent Baerveldt Implant Surgery at the Japanese Red Cross Medical Center, Tokyo, Japan. METHODS Pre- and postoperative intraocular pressure (IOP), combined surgery, po...

A 74-year-old woman presented with a 3-month history of right facial ache radiating to the right forehead and temporal region. Three weeks prior to presentation the left eye became red and irritated and binocular horizontal diplopia developed. CT demonstrated a dilated left superior ophthalmic vein. The patient was referred for neuroophthalmic evaluation. Medical and surgical history included h...

BACKGROUND We present a rare case of secondary angle closure glaucoma due to systemic lupus erythematosus choroidopathy as initial presentation of systemic lupus erythematosus, accompanied by central nervous system vasculitis and uncontrolled nephropathy. CASE PRESENTATION A 31-year-old woman presented with decreased visual acuity, nausea, vomiting, fever, and bilateral angioedema-like eyelid...

Nonarteritic anterior ischemic optic neuropathy (NAION) has been the subject of numerous publications and editorials. Yet, meaningful progress toward understanding the pathogenesis of this entity has been limited. As the term “ischemic” would indicate, investigators have focused their efforts on defending a vascular cause. What is the evidence for ischemia in this entity that, by histopathologi...

OBJECTIVE To assess outcomes of proton beam radiotherapy for the treatment of extra-large uveal melanomas in patients specifically referred to the University of California, San Francisco, for ocular conservation therapy. Series patients uniformly refused enucleation both at an outside institution and again as a treatment option after extensive discussion at the University of California, San Fra...

A case of uveal malignant melanoma and contralateral optic nerve glioma is described in a 53-year-old Caucasian male with multiple uveal melanocytic hamartomas and neurofibromatosis. The eye was enucleated, and histologically the melanoma was found to consist of 70% epithelioid cells, with many bizarre, multinucleated forms. CT scan demonstrated a non-enhancing, fusiform enlargement of the cont...