Inhaled-nitric oxide (NO) is a selective pulmonary vasodilator in short-term clinical studies. Use of NO inhalation in chronic pulmonary hypertension is complicated by potential problems with ambulatory NO delivery. We hypothesized that long-term infusion of NO solution into the central venous circulation, which did not suffer from this drawback, might reduce chronic pulmonary hypertension. Sat...

evidence acquisition elevated serum leptin levels are regarded as an established marker of obesity. it is also reported that obese asthmatic patients have maximum serum leptin levels compared to other groups such as non-obese asthmatics, and normal obese and non obese subjects without asthma. in addition to having an appetite suppressing effect, leptin also regulates certain acute-phase protein...

background: resistive inspiratory muscle training (rimt) is a well-known technique for rehabilitation of patients with chronic obstructive pulmonary disease (copd). incentive spirometry is another technique with potential viability for this application, but there is limited evidence in support of its efficacy in the rehabilitation of copd patients. aim: the objective of this study was to compar...

Pulmonary concerns in liver transplant candidates have intraoperative and outcome implications. Evolving MELD exception policies address transplant priority for problems such as hepatopulmonary syndrome, portopulmonary hypertension, and hemorrhagic hereditary telangiectasia. Other pulmonary issues such as refractory hepatic hydrothorax, advanced chronic obstructive lung disease (including alpha...

Background: Chronic Pulmonary Aspergillosis (CPA) is a destructive pulmonary disease caused by fungal infection, frequent complication

This article reviews a selection of presentations in the area of clinical problems that were presented at the 2014 European Respiratory Society International Congress in Munich, Germany. We review the most recent and relevant topics of interest in the area of clinical respiratory medicine, encompassing novel reports and studies that are of particular interest to healthcare professionals. Topics...

Hemodynamically significant patent ductus arteriosus (hs-PDA) is a common cause of morbidity and mortality among preterm infants, affecting more than 40% infants. A persistent hs-PDA can problems, especially in premature Thus, the early closure important to prevent several comorbidities such as necrotizing enterocolitis (NEC), intraventricular hemorrhage (IVH), pulmonary edema/hemorrhage, devel...