Acute mountain sickness (AMS) is a clinical syndrome occurring in otherwise healthy normal individuals who ascend rapidly to high altitude. Symptoms develop over a period ofa few hours or days. The usual symptoms include headache, anorexia, nausea, vomiting, lethargy, unsteadiness of gait, undue dyspnoea on moderate exertion and interrupted sleep. AMS is unrelated to physical fitness, sex or ag...

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Acute mountain sickness is the commonest acute high altitude illness occurring at high altitude. Its prevalence is dependent on the ascent rate, altitude achieved, physical effort required to reach the target altitude and pharmacological intervention undertaken by the tourists visiting high altitude areas. This Letter to the Editor is an endeavour to re-emphasise the importance of all these fac...

A double blind, randomised, placebo controlled trial of treatment with dexamethasone for acute mountain sickness was performed in the Capanna "Regina Margherita" at an altitude of 4559 m in the Alps Valais. After 12-16 hours of treatment (8 mg dexamethasone initially, followed by 4 mg every six hours) the mean acute mountain sickness score decreased significantly from 5.4 to 1.3, and eight of 1...

The heart rate response to exercise was studied in 17 normal subjects before, during and after a 21-day Himalayan trek to 5490 m. The group were fitter before the trek when compared to normal subjects of a similar age (P less than 0.001) having a lower heart rate response to exercise for their lean body mass. The trek significantly increased the 'fitness' of the group as a whole (P less than 0....

Villafuerte, Francisco C., and Noemí Corante. Chronic mountain sickness: clinical aspects, etiology, management, and treatment. High Alt Med Biol. 17:61-69, 2016.-Millions of people worldwide live at a high altitude, and a significant number are at risk of developing Chronic Mountain Sickness (CMS), a progressive incapacitating syndrome caused by lifelong exposure to hypoxia. CMS is characteriz...

Its probable first account has been given by Plutarch in his comments on Alexander’s invasion of India: “Many then were the dangers— but the greatest harm came from severity of weathers”. Similarly, a Chinese record mentions of “Lesser Headache Mountains” and the “Greater Headache Mountains” where men’s bodies become feverish, they lose color and are attacked with headache, dizziness and vomiti...