Aging is associated with an increase in a chronic, low-grade inflammation. This phenomenon, termed "inflammaging" is also a risk factor for both morbidity and mortality in the elderly. Frequent co-occurrence of chronic diseases, known as multi-morbidity, may be explained by interconnected pathophysiology of these conditions, most of which depend on its inflammatory component. Here we present an...

The rate of psychiatric morbidity in medical in-patients suffering from chronic physical illness is reported to be quite high. In this study, patients with chronic medical illness showed psychiatric morbidity at the rate of 52.5%. According to DSM-IV criteria, the most common diagnosable psychiatric disorder was depressive disorder- 25% mild, 65% moderate and 10% severe. There were significant ...

Chronic hepatitis B remains a major public health concern and leading cause of morbidity mortality worldwide, specifically through its causative role in chronic liver disease hepatocellular carcinoma. Worldwide, it affects up to 292 million people. In this paper, we review the historic discovery virus chronicle significant advances our understanding interactions with human host disease. We also...

Chronic kidney disease (CKD) has grown to be a global and public health concern due the increasing number of patients receiving renal services its economic burden on healthcare system in terms increased costs. CKD also is associated with unfavorable outcomes raised morbidity mortality rates.

Anemia is the most common complication of chronic kidney disease (CKD) associated with reduced quality life and increased morbidity mortality. The purpose this review was to discuss management anemia in CKD. following topics are considered: prevalence anemia, symptoms, impact CKD, diagnosis, iron replacement therapy, erythropoiesis-stimulating agents.

objectives: the purpose of this multi-center study was to investigate the probable predictive factors of mortality and morbidity in elderlypopulation. methods & materials: the descriptive prospective study was conducted based on the data gathered from trauma cases older than 65 years admitted to sina, shohada and fayaz-bakhsh trauma centers during years 1997-98. a pre-prepared questionnaire inc...

traumatic brain injury (tbi) is a significant public health concern in our country, because of placing in top three most common causes of death and substantial direct and indirect costs to society. the incidence of tbi in our country is 1.7 times of international incidence. traumatic brain injury induced by primary and secondary mechanisms that give rise to death and neurologic morbidity in pat...

OBJECTIVE To assess the effectiveness of different modes of treatment of chronic anal fissure as regards improvement of symptoms and complications. METHODS This prospective study included 129 consecutive patients with chronic anal fissures presented to the Surgical Outpatients' Department of Islam Teaching Hospital Sialkot, Pakistan; from September 2010 to November 2012. Patients were distrib...

T1HE recent emphasis on early surgical intervention for patients with chronic rheumatic valvular disease has made the need for basic data concerning the natural history of this conditioii of practical importance. Data regarding the natural morbidity of patients with chronic rheumatic heart disease in the third, fourth, and fifth decades of life are presented. This information should prove usefu...

Sepsis in pregnancy and the puerperium remains a significant cause of maternal mortality and morbidity worldwide. Major morbidity arising as a result of obstetric sepsis includes fetal demise, organ failure, chronic pelvic inflammatory disease, chronic pelvic pain, bilateral tubal occlusion and infertility. Early recognition and timely response are key to ensuring good outcome. This review exam...