The use of CE in the analysis of pharmaceuticals is now becoming Rrmly established as a useful complement and alternative to the more widely employed technique of HPLC. The major attractions of CE are that considerable cost and time savings are possible, especially in the areas of chiral analysis and in the determination of solutes having limited or no chromophore. The recent advent of the use ...

High performance liquid chromatography (HPLC) is often the method of choice for the separation of nonvolatile solutes. LC commonly exhibits longer analysis times, larger pressure drops and lower efRciency than either supercritical Suid chromatography (SFC) or gas chromatography (GC). The greater viscosities and lower diffusivities of liquids compared to those of supercritical Suids or gases are...

spheric pressure ionization mass spectrometric analysis of new anionic surfactants: the alkylpolyglucoside esters. Journal of the American Oil Chemists’ Society 72: 1}9. Metcalfe LD (1962) Potentiometric titration of long chain amine oxides using alkyl halide to remove tertiary amine interference. Analytical Chemistry 34: 1849. Milwidsky BM and Gabriel DM (1982) Detergent Analysis. New York: Ha...

Citrus essential oils are very complex matrices which contain numerous compounds of different chemical classes. These compounds are generally divided into two fractions: the volatile fraction, which is the most representative, and ranges between 85 and 99% in the different cold-pressed citrus oils, and the non-volatile residue, which ranges between 1 and 15%. The development of new instrumental...

Many proteins in cells and biological Suids are glycosylated, and these glycoproteins are present in animals, plants, microorganisms and viruses. The most commonly occurring monosaccharides found in oligosaccharide attachments to mammalian proteins are D-mannose (Man), D-galactose (Gal), D-glucose (Glu), L-fucose (Fuc), N-acetylglucosamine (GlcNAc), N-acetylgalactosamine (GalNAc), and Nacetylne...

Online comprehensive two-dimensional liquid chromatography has become an attractive option for the analysis of complex nonvolatile samples found in various fields (e.g. environmental studies, food, life, and polymer sciences). Two-dimensional liquid chromatography complements the highly popular hyphenated systems that combine liquid chromatography with mass spectrometry. Two-dimensional liquid ...

On-chip liquid chromatography (LC) refers to LC technology that is miniaturized fit on a microchip enable fast, high-throughput analysis, with small sample volumes and low reagent consumption. Four different on-chip approaches have been developed date: use of open-tubular, packed-particle, monolithic, pillar array columns. These methods applied proteomics as well the analysis molecules drugs in...