450-5 m,u.)since it yielded a singleband on mixed chromatography with cryptoxanthin obtained from yellow maize (Sadana, 1946). Zone II. This was an orange-coloured band. The pigment was identified as neo-,-carotene U (maxima in light petroleum 480 and 450 mp.; Sadana, 1949). Zone III. This was reddish orange in colour. The pigment was extracted and identified as $-carotene by its absorption spe...

Collection of sebum. Samples of the sebum were obtained (Miescher & Schonberg, 1949) from the forehead of healthy white adults 16-60 years of age. Samples were analysed from 21 persons (11 men, 10 women) not suffering from skin diseases. To collect the sample, a strip of filter paper (Whatman no. 1, 3 cm. x 12 cm.), previously defatted by extraction with boiling light petroleum, was placed on t...

Background: Woodfordia fruticosa is used traditionally as antidysenteric compound for fodder animals. Stem and flower extracts are previously flourished for their antibacterial activity. Leaves are also equally important, which are preliminary screened for their bioactive components in present study. Objective: Evaluation of antibacterial activity of leaves of W. fruticosa and detection of the...

Citrullus colocynthis (L.) (C. colocynthis), commonly known as Handal in Yemen and other Arabic countries, is a plant with wide range of pharmacological properties. These properties are attributed to secondary metabolites, phytochemicals, present the plant. In this study, seed C. were extracted using dichloromethane, resulting oil extract was screened identify active phytoconstituents gas chrom...

2120 CLINICAL CHEMISTRY, Vol. 40, No. 11, 1994 we reported here, we overcome this problem by using the filters. We have not observed any late-eluting peaks that would interfere with the subsequent chromatogram nor any reduction in column life attributable to sample contamination. Moreover, the results we obtained with the amperometric detector are comparable with those of the coulometric detector.

Abbreviations: LLOQ: Lower Limit of Quantification; QC: Quality Control; LQC: Low QC; MQC: Middle QC; HQC: High QC; SPE: Solid Phase Extraction; MRM: Multiple Reaction Monitoring; CV: Coefficient of Variation; RE: Relative Error; QqTOF: Quadrupole-QuadrupoleTime-Of-Flight; FDA: Food and Drug Administration; EMA: European Medicines Agency; XIC: Extracted-Ion Chromatogram; AUC: Area under the Cur...

Mutagenic activity was found in the urine of 10 patients given therapeutic dosages of metronidazole orally or per vagina. Paper chromatographic separation revealed that mutagenicity in the urine was associated with unmodified metronidazole and at least four of its known urinary metabolites. Activity was also recovered in a region of the chromatogram heretofore not assigned to a metronidazole me...