Objective: To investigate the cumulative recurrence rate of pars tensa retraction cholesteatoma on the new staging system established by Japan Otological Society (JOS). Materials and Methods: It is a retrospective study and performed in a tertiary and academic center. The series comprised 71 patients with pars tensa retraction cholesteatoma who underwent surgical treatment by a single surgeon b...

The classic presentation of congenital cholesteatoma is a pearl behind the anterior-superior quadrant of an intact tympanic membrane. Idiopathic hemotympanum is characterized by a dark blue eardrum, the most prominent feature of which is the presence of cholesterol granulomas. Blue eardrum is associated with eustachian tube dysfunction. Despite the well-established relationship between eustachi...

External ear canal cholesteatoma (EAC) is a rare destructive lesion within temporal bone and may occur in 1:1000 new patients with ear diseases [1, 3]. EAC cholesteatoma was first described by Toynbee in 1850. Since that time, it had confused to keratosis obturans. First description of keratosis obturans was presented by Piepergerdes et al., in 1980 [6]. Keratosis obturans (KO) is a similar to ...

OBJECTIVES/HYPOTHESIS To review the recent cell proliferation signal pathways in the etiopathogenesis of acquired middle ear cholesteatoma. DATA SOURCES PubMed (to September 2015). REVIEW METHODS Articles about cell proliferation signal pathways in the etiopathogenesis of acquired cholesteatoma and treatment advances were searched in the PubMed database, from which 73 were included in this ...

OBJECTIVES 1. To investigate whether systematic preservation of the intact ossicular chain in cholesteatoma surgery provides better hearing than dismantling the chain and reconstructing it. 2. To determine whether systematic preservation of the ossicular chain in cholesteatoma surgery can be performed safely. STUDY DESIGN Longitudinal parallel group study. SETTING District general hospital ...

INTRODUCTION Recently published data indicate that over 60% of patients with middle ear cholesteatoma (MEC) have concomitant changes in the contralateral ear (CE). Studies concerning the condition of the CE are few and rarely present the situation in the pediatric population. THE AIM OF THIS STUDY was to assess the frequency of pathological changes occurring in the CE in children operated on ...

OBJECTIVE To study the state of proliferation and apoptotic cell death in cholesteatoma. METHOD 20 cholesteatoma samples and 10 normal external ear canal skin samples were studied with immunohistochemical SABC technique and TUNEL technique. RESULT Immunohistochemical analysis using a monoclonal antibody to proliferation cell nuclear antigen (PCNA) demonstrated the presence of proliferating ...

BACKGROUND Extrdural granulation or abscess is a possible complication of chronic suppurative otitis media (CSOM) with cholesteatoma. However, due to development of newer antibiotics and advances in bacteriology and imaging techniques, the incidence of extradural granulation or abscess has significantly decreased. The present study analyzed the clinical presentation, imaging findings, and surgi...

In this paper, we report the postoperative outcomes in canal wall up procedures with second stage surgery in 40 children undergoing intervention for cholesteatoma of the middle ear. The residuals, recurrences and the hearing results were analysed. All 40 patients had a follow-up of at least five years. Of the 39 patients who underwent two staged surgery, 18 (46.1%) had a residual lesion that wa...