نتایج جستجو برای: cholecystokinin antagonist

تعداد نتایج: 61860  

Journal: :Gut 1993
R Fraser D Fone M Horowitz J Dent

Stimulation of localised pyloric contractions may be an important mechanism in the slowing of gastric emptying by cholecystokinin infusion. The effect of cholecystokinin octapeptide on fasting pyloric motility was investigated in 14 healthy volunteers. Antral, pyloric, and duodenal pressure responses to normal saline and graded injections of cholecystokinin octapeptide (5, 10, and 20 ng/kg) wer...

Journal: :Gut 1982
E L Giannoulis R E Barry

An in vitro bioassay for cholecystokinin which is superior to the previously described in vivo assays has been properly validated mathematically. The specificity of the assay has been assessed by measuring the potency of other polypeptides which share the same C-terminal pentapeptide sequence with cholecystokinin (gastrin, caerulin, octapeptide of cholecystokinin, and pentagastrin). The assay i...

2005
Jacqueline R. McDermott Fiona C. Leslie Massimo D’Amato David G. Thompson Richard K. Grencis John T. McLaughlin

Background and aims: Gastrointestinal inflammation reduces food intake, but the biological mechanisms explaining suppressed feeding during inflammation are unknown. We have used a model of upper gut infection (Trichinella spiralis in the mouse) to study the effect of inflammation on food intake, and explored the role of a key enteroendocrine cell (EEC) in the regulation of feeding by the immune...

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