Following sexual transmission, Chlamydia trachomatis specifically targets genital tract epithelial cells. Because epithelial cells are readily recognized by CD8+ T cells, the response of CD8+ T cells to Chlamydia infection has been explored in a number of studies. It has been shown that CD8+ T cells are present in the genital tracts of mice following C. trachomatis infection, but the specificit...

Chlamydia trachomatis is an important human pathogen that replicates inside the infected host cell in a unique vacuole, the inclusion. The formation of this intracellular bacterial niche is essential for productive Chlamydia infections. Despite its importance for Chlamydia biology, a holistic view on the protein composition of the inclusion, including its membrane, is currently missing. Here we...

Background: We designed a prospective study to assess the role of Chlamydia in secondary infertility Materials and Methods: 40 women with secondary infertility and 30 term healthy pregnant women of similar age composition were studied for past and present chlamydia trachomatis infection. Women attending the outpatient department of Obstetrics and Gynaecology with complaint of secondary infertil...

Citation: Parolin C, Foschi C, Laghi L, Zhu C, Banzola N, Gaspari V, D’Antuono A, Giordani B, Severgnini M, Consolandi C, Salvo M, Cevenini R, Vitali B and Marangoni A (2018) Insights Into Vaginal Bacterial Communities and Metabolic Profiles of Chlamydia trachomatis Infection: Positioning Between Eubiosis and Dysbiosis. Front. Microbiol. 9:600. doi: 10.3389/fmicb.2018.00600 Insights Into Vagina...

Asymptomatic Chlamydia trachomatis infections may represent an important reservoir for the agent and treating patients who have symptoms along with their partners may not be eVective in reducing the prevalence of C trachomatis infection. The aim of this study was to estimate the incidence of C trachomatis genital infection in a young population attending an anonymous and free HIV test centre an...

Sexually transmitted infections (STIs) represent a worldwide public health burden, but many and diseases continue to be neglected. Areas with low human development index, including the northern areas of Brazil, particularly immense geographic Amazon region, present high frequency STIs because variables that contribute disseminate infection, lack access education, prevention measures treatment t...

BACKGROUND The focus of Chlamydia trachomatis screening and testing lies more on women than on men. The study aim was to establish by systematic review the prevalence of urogenital Chlamydia trachomatis infection in men and women in the general population. METHODS Electronic databases and reference lists were searched from 2000 to 2013 using the key words "Chlamydia trachomatis", "population-...

background: chlamydia trachomatis (ct) is a common cause of sexually transmitted infections (sti) and a prevalent microorganism found in the vaginal discharge of sexually active women. the infection usually has no symptoms; although it may cause chronic complications such as pelvic inflammatory disease (pid), ectopic pregnancy, chronic pelvic pain, tubal infertility and cervical cancer. this st...

OBJECTIVES To identify Chlamydia trachomatis via polymerase chain reaction and a direct fluorescent antibody assay in patients with vernal keratoconjunctivitis while comparing the efficacies of both tests for detecting Chlamydia trachomatis in these conditions. METHODS Conjunctival scraping samples were obtained from 177 patients who were divided into two groups: a vernal keratoconjunctivitis...

Since genital infection with Chlamydia trachomatis may be associated with cervical abnormalities 160 patients with grandular ectopia attending a gynaecological outpatient clinic were examined for antibodies against C trachomatis, the presence of C trachomatis infection, and cytological and histopathological abnormalities of the cervix.A significantly higher incidence of histological dysplasia w...