Crystalline chitosan was successfully prepared from crab tendons with aligned chitin molecules. Chitosan obtained preserved the tube structure with a suitable size for nerve conduits (t-chitosan tube). The chitosan tubes were compounded with hydroxy apatite (HAp) using an alternate soaking method (t-chitosan/HAp tube) to enhance the strength of the tube walls. HAp crystals formed in the walls o...

Radiation is one of the most widespread sources of environmental stress in living environment which cause oxidative stress and metabolic changes. Chitosan is widely distributed in nature as a component of bacterial cell walls and exoskeletons of crustaceans and insects. The present study aims to evaluate the antioxidant effect of chitosan against gamma rays induced oxidative stress and metaboli...

a bionanocomposite film was developed by nanoclay incorporation to chitosan films, using a solution casting method and the effects of nanoclay concentration (0.5, 1.0, and 3% w/w) on the physical and mechanical properties of the chitosan films were evaluated. moreover, x-ray diffraction (xrd), scanning electron microscopy, and fourier transform infrared spectra (ftir) were used for studying mic...

The glucose oxidase (GOx) enzyme was immobilized on chitosan-based porous composite membranes using a covalent bond between GOx and the chitosan membrane. The chitosan-based porous membranes were prepared by the combination of the evaporation- and non-solvent-induced phase separation methods. To increase the membrane conductivity, carbon nanotubes (CNTs) were added to the chitosan solution. The...

Hybrid nanofibrous membranes of poly(lactic-co-glycolic acid) (PLGA) and chitosan with different chitosan amounts (32.3, 62.7, and 86.5%) were fabricated via a specially designed electrospinning setup consisting of two sets of separate syringe pumps and power supplies. After soaking in chloroform overnight to dissolve PLGA, the amount of chitosan in the hybrid membranes was determined. The stru...

OBJECTIVES Chitosan has been widely investigated and used. However, the literature does not refer to the shelf life of this solution. This study evaluated, through the colorimetric titration technique and an analysis of dentin micro-hardness, the shelf life of 0.2% chitosan solution. MATERIALS AND METHODS Thirty human canines were sectioned, and specimens were obtained from the second and thi...

BACKGROUND Chitosan, a linear polysaccharide, has been recently used in biomedical applications. In vitro studies have demonstrated its effect on cellular growth and its stimulatory action on cellular layer formation. AIMS The present study aims to compare the proliferative effects of chitosan in two forms, membranous and solution forms, on Swiss 3T3 mouse embryonic fibroblasts. STUDY DESIG...

Chitosan, a natural polysaccharide, has increasingly been studied as an adsorbent for heavy metal removal in recent years. The amine groups in chitosan are generally known to be the main adsorption sites for heavy metal ions. However, due to the instability of chitosan in acidic solutions, chemical crosslinking has often been used to enhance the acidic resistance of the material. Since most of ...

Novel poly(L-lactic acid) (PLLA)-chitosan hybrid scaffolds were developed in order to be used as tissue-engineering scaffolds and drug release carriers. The incorporation of chitosan into the PLLA porous structure allows for producing chitosan-based scaffold devices with interesting damping and stiffness aimed at being used in tissue engineering of bone or cartilage. The pore structure of the h...

This in vitro study investigated the metabolism of human osteoarthritic (OA) chondrocytes encapsulated in a spherical matrix enriched of chitosan. Human OA chondrocytes were encapsulated and cultured for 28 days either in chitosan-alginate beads or in alginate beads. The beads were formed by slowly passing dropwise either the chitosan 0.6%-alginate 1.2% or the alginate 1.2% solution through a s...