Natural compounds can exist in different forms, where molecules possessing chirality play an essential role living organisms. Currently, one of the most important tasks modern analytical chemistry is enantioseparation chiral compounds, particular, enantiomers having biological and/or pharmaceutical activity. Whether task to analyze environmental or food samples develop assay for drug control, w...

REVIEWS This review covers developments and applications in chiral separations from January 2000 to March 2002. This review is not intended to be a comprehensive review of all papers published, but focuses on major developments in the field of chiral separations as well as representative applications. The review is restricted to the English language literature except as noted for several specif...

Many substances of forensic interest are chiral and available either as racemates or pure enantiomers. Application of chiral analysis in biological samples can be useful for the determination of legal or illicit drugs consumption or interpretation of unexpected toxicological effects. Chiral substances can also be found in environmental samples and revealed to be useful for determination of comm...

Enantioseparation is largely based on the formation of transitional complexes, the solvation species, the stationary phase configurations or the diastereomeric complexes formed by analytes and the chiral stationary phase. Temperature and the chemical nature and composition of the eluent play significant roles during that process. In this study; unique temperature-induced behaviors were observed...

We synthesized 3-(4-sulfo-1,8-naphthalimido)propyl-modified silica (SNAIP) for capillary electrochromatography (CEC). The unique structure of SNAIP contributed to the retention by three interactions including hydrophobic, electrostatic and interactions and the acceleration of electroosmotic flow at an acidic condition. The CEC employing SNAIP was successively applied to the rapid separations of...

the high performance liquid chromatography (hplc) enantioseparation of four β-blocking agents metoprolol, bisoprolol, propranolol and atenolol was performed on amylose tris-(3,5-dimethylphenylcarbamate) chiral stationary phase using n-hexane-ethanol-diethylamine (dea) as the mobile phase and related chiral recognition mechanisms were discussed. enantiomeric separation of the fourβ-blockers was ...

The high performance liquid chromatography (HPLC) enantioseparation of four β-blocking agents metoprolol, bisoprolol, propranolol and atenolol was performed on amylose tris-(3,5-dimethylphenylcarbamate) chiral stationary phase using n-hexane-ethanol-diethylamine (DEA) as the mobile phase and related chiral recognition mechanisms were discussed. Enantiomeric separation of the fourβ-blockers was ...