The tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) has been reported to act as a cancer preventive agent through folate pathway inhibition in experimental studies. We hypothesized that if folate pathway inhibition is the mechanism of cancer preventive activities of EGCG, then the protective effect against breast cancer would be stronger among women with low dietary folate intake and the h...

For more than 1000 years green tea has been used in China and Japan as a medical herb and a healthful beverage. The traditional Chinese medicine has recommended this plant for headaches, body aches and pains, digestion, depression, detoxification, as an energizer and, in general, to prolong life. Tea is made from young shoots and leaves of the plant Camellia sinensis (Willson and Clifford 1992;...

background: exercise and consumption of green tea affect the aging process. however, the effect of exercise training combined with green tea extract on leukocyte telomere length, quality of life (qol) and body composition in aging has so far been unclear and inconsistent. objective: the aim of the present study was to determine the effectiveness of aerobic training intervention and green tea ex...

Tea is the second most consumed beverage in the world, following water. Black, oolong, and green tea are products of a perennial tree or shrub called Camellia sinensis. Camellia sinensis is native to Mainland China and is referenced in Chinese literature at least 5000 years ago. Since its discovery, green tea has been heralded as having several health benefits associated with its consumption. T...

To date quality and selling price of a tea mainly depends on its flavour, taste and texture but not on its medicinal properties though a Chinese scientist in 780 AD suggested and acclaimed tea as a divine remedy and supreme gift of God for preserving mental tranquillity. Different studies have been showed that L-theanine is the key component of tea which can make us mentally calm, cool and rela...

There is substantial in vitro and in vivo evidence implicating tea polyphenols as chemopreventive agents against various cancers. In a case-control study conducted among Asian-American women in Los Angeles County, we reported a significant inverse relationship between intake of green tea and risk of breast cancer (A. H. Wu et al., Int. J. Cancer, 106: 574-579, 2003). Because catechol-containing...

Over the past decade, teas and their molecular components have received increasing attention from researchers in human health. After water, tea is the most widely consumed and popular beverage in the world. It has a cooling effect, slightly bitter and astringent flavor which many is enjoyed by people and its medicinal properties have been widely explored. In addition, its content of certain min...

Tannic acid presents in varying concentrations in plant foods, and in relatively high concentrations in green teas and red wines. Human ether-à-go-go-related gene (hERG) channels expressed in multiple tissues (e.g. heart, neurons, smooth muscle and cancer cells), and play important roles in modulating cardiac action potential repolarization and tumor cell biology. The present study investigated...

Intestinal epithelial cells (IECs) have been known to produce galactose-alpha1,4-galactose-beta1,4-glucose ceramide (Gb3) that play an important role in the mucosal immune response. The regulation of Gb3 is important to prevent tissue damage causing shiga like toxin. Epigallocatechin-3-gallate (EGCG) has been studied as anti-carcinogenic, anti-oxidant, anti-angiogenic, and anti-viral activities...

BACKGROUND Tea has long been believed to possess hypotensive effects in popular Chinese medicine. However, conflicting results have been shown among human trials and animal studies on the relation between tea consumption and blood pressure. Epidemiological evidence about the long-term effect of tea on hypertensive risk is also inconsistent. METHODS We examined the effect of tea drinking, meas...