Background The impact of cancer therapy on the reproductive potential of patients is increasingly recognized because survival rates of patients have clearly improved in recent years. The study stressed the use of AMH may allow better prediction of chemotherapy-related risk to further fertility. MaterialsAndMethods A narrative review was performed within articles published at PubMed, Elsevier, S...

There has been a dramatic increase in the number of childhood cancer survivors living to an old age due to improved cancer treatments. However, these survivors are at risk of numerous late effects as a result of their cancer therapy. Engaging in protective health behaviors and limiting health damaging behaviors are vitally important for these survivors given their increased risks. We reviewed t...

The causes of childhood cancer have been systematically studied for decades, but apart from high-dose radiation and prior chemotherapy there are few strong external risk factors. However, inherent risk factors including birth weight, parental age, and congenital anomalies are consistently associated with most types of pediatric cancer. Recently the contribution of common genetic variation to et...

Abnormalities of the thyroid gland are among the most frequent endocrine complications observed in childhood cancer survivors. We report an 11 years old girl who developed central hypothyroidism and ACTH deficiency during the chemotherapy for CNS relapse of acute lymphoblastic leukemia before receiving radiotherapy. Keywords: Thyroid gland, hypothyroidism, chemotherapy, acute lymphoblastic leu...

In 2007, almost 10,400 American children younger than 15 years were diagnosed with cancer, with approximately 1,545 dying from the disease (National Cancer Institute, 2009). In Britain, the risk of a child younger than 15 years being diagnosed with cancer is about 1 in 500 (Cancer Research UK, 2009). Significant improvements have been made in five-year relative survival from childhood cancers, ...

My 12-year-old daughter recently visited Children’s Hospital on a school field trip for science class. Although the purpose of the visit was to peer into the microscopes in the hospital laboratory, my daughter and her classmates saw several children in the waiting areas and hallways. Many were presumably being treated for cancer, which prompted the class’s collective response of “it’s so sad, s...

Cancer is diagnosed in about 140 per million children in Britain each year. There is a 1 in 500 chance that a child will be affected in the first 15 years of life, the most frequently occurring types of cancer being leukaemia and brain tumours. This book covers the descriptive epidemiology of childhood cancer in Britain, based on the unique work of the National Registry of Childhood Tumours, th...

Sins of the Father ParentalSmoking and Childhood Cancer Exposure to passive (or environmental) tobacco smoke has been implicated in numerous childhood ailments ranging from low birth weight to middle ear disease. Passive smoke has also been suspected, but not proven, to increase the risk of childhood cancer. Clarifying this issue is crucial not only for the protection of children's health but a...

Sins of the Father ParentalSmoking and Childhood Cancer Exposure to passive (or environmental) tobacco smoke has been implicated in numerous childhood ailments ranging from low birth weight to middle ear disease. Passive smoke has also been suspected, but not proven, to increase the risk of childhood cancer. Clarifying this issue is crucial not only for the protection of children's health but a...