BACKGROUND Evidence has suggested that periodontal disease is associated with an increased risk of various adverse pregnancy and birth outcomes. However, several large clinical randomized controlled trials failed to demonstrate periodontal therapy during pregnancy reduced the incidence of adverse pregnancy and birth outcomes. It has been suggested that the pre-conception period may be an optima...

BACKGROUND Dexmedetomidine can facilitate a smooth extubation process and reduce the requirement of sevoflurane and emergence agitation when administrated perioperatively. We aimed to observe the extubation process and the recovery characteristics in pediatric patients undergoing tonsillectomy while anesthetized with either high-concentration sevoflurane alone or low-concentration sevoflurane c...

BACKGROUND The primary objective of this study was to assess whether Zhengtian Capsule was non-inferior to flunarizine in efficacy and safety profile for prevention of migraine in adults. METHODS This was a double-dummy, double-blind, multicenter, positive drug (flunarizine), parallel randomized controlled, non-inferior clinical trial. Patients (n = 360) were randomized in a 1:1 to receive ei...

BACKGROUND That patients with acute radiculopathy caused by lumbar disc herniation (LDH) will benefit from spinal manipulation (SM) treatment has been taken for granted, despite no solid evidence to support that claim. There is a demand for a win-win SM treatment that is both effective and less risky, and we attempt to use this trial to demonstrate such a treatment. In this study, Feng's Spinal...

BACKGROUND In Traditional Chinese Medicine (TCM) theory, functional dyspepsia (FD) can be divided into different syndromes according to different clinical symptoms and signs, and the most common one is spleen-deficiency and qi-stagnation syndrome that can be treated by Chinese traditional patent medicine--two kinds of Zhizhu pills, between which the primary difference in ingredients is that one...

BACKGROUND College students and working adults are particularly vulnerable to stress and other mental health problems, and mental health promotion and prevention are needed to promote their mental health. In recent decades, mindfulness-based training has demonstrated to be efficacious in treating physical and psychological conditions. OBJECTIVE The aim of our study was to examine the efficacy...

Abstract Background Surgery is a potential trigger of Guillain-Barré syndrome (GBS), disorder which leads to an autoimmune-mediated attack peripheral nerves. The present study was designed explore clinical features post-surgical GBS compared with those general in order provide better advice patients undergoing surgery. Methods medical records who were seen at 31 tertiary hospitals southern Chin...

Abstract Background More than 50% cognitive impairment was reported by cancer patients before and after medical treatment. However, there are no effective interventions to manage the problem in women with breast cancer. This pilot study designed evaluate protective effect of Baduanjin exercise on function cancer-related symptoms early-stage undergoing chemotherapy. Method A single-blinded, rand...

Abstract Background The National Chest Pain Center Accreditation Program (CHANGE) is the first hospital-based, multifaceted, nationwide quality improvement (QI) initiative, to monitor and improve of ST segment elevation myocardial infarction (STEMI) care in China. QI initiatives, as implementation strategies, include a bundle evidence-based interventions adapted for During pandemic coronavirus ...

Abstract Background Ankylosing spondylitis (AS), as a common inflammatory rheumatic disease, often causes depression and impaired health-related quality of life (QoL). Although positive effects patient education have been demonstrated, limited studies explored the benefits via mobile applications for AS patients. This study aimed to evaluate WeChat-based educational intervention on depression, ...