BACKGROUND Oesophageal acid neutralization with antacids depends on the duration of oesophageal antacid exposure and acid neutralizing capacity. A gum that releases antacid as it is chewed could take advantage of both mechanisms to enhance heartburn relief. METHODS Twenty-four subjects were crossed over to four regimens: placebo, chewable antacid tablets (1000 mg CaCO3), lower dose gum (600 m...

Ion exchange resins are water-insoluble, cross-linked polymers containing salt-forming groups in repeating positions on the polymer chain. Bitter cationic drugs get adsorbed on to weak cationic exchange resins of carboxylic acid functionality like Indion 204, Indion 234 and Tulsion 335 to forms non-bitter complexes. The present investigation aims at taste masking of the bitter clarithromycin us...

After launching of Sildenafil Citrate, the last invention of 20 century, in 1998, oral PDE5 inhibitor has been established as first line treatment of erectile dysfunction (ED) and shift new paradigm of diagnosis and treatment of ED. The big success of sildenafil in pharmaceutical R&D induced the consecutive development S28 Translational Andrology and Urology, Vol 4, Suppl 1 August 2015 © Transl...

© Translational Andrology and Urology. All rights reserved. Transl Androl Urol, 2015;4(S1) www.amepc.org/tau of the so-called ‘The second viagra’, e.g., Tadalafil and Vardenafil in 2003. Currently, these 3 kinds of PDE5 inhibitors are most famous and well-known PDE5 inhibitors worldwide. In Korea, another 3 kinds of PDE5 inhibitors, Udenafil (2005), Mirodenafil (2007) and Avanafil (2011) have b...

Introduction Conclusions References

A trace amount of metal carbonate, acetate or borate significantly boosts gold nanocatalysts in selective aerobic oxidation of alcohols under mild solvent-free conditions.

McKay et al. [(1996) Science 273, 924-930] suggested that carbonate globules in the meteorite ALH84001 contained the fossil remains of Martian microbes. We have characterized a subpopulation of magnetite (Fe(3)O(4)) crystals present in abundance within the Fe-rich rims of these carbonate globules. We find these Martian magnetites to be both chemically and physically identical to terrestrial, bi...