The spontaneous resolution of herniated cervical discs has not been previously well documented. The authors analysed four cases who underwent spontaneous resolution of herniated cervical discs, and all other cases reported in the literature. A complex physiopathologic mechanism that includes the release of basic fibroblast grow factors, endothelial cell proliferation, chemotaxis of inflammatory...

The leukotrienes are potent lipid mediators of inflammation formed by the 5-lipoxygenase-catalyzed oxidation of arachidonic acid. Although the effects of leukotrienes on neutrophil chemotaxis and activation have been established, their role in modulating innate host defense mechanisms is poorly understood. In a previous study (M. Bailie, T. Standiford, L. Laichalk, M. Coffey, R. Strieter, and M...

Random migration, chemotaxis, phagocytosis, and bactericidal ability of neutrophils from 5 patients receiving lithium carbonate were compared with those of neutrophils from healthy donors. These cells functioned normally in all respects. Neither sera from patients receiving lithium carbonate nor the addition of lithium chloride to control cells in vitro significantly altered their functional ca...

antibiotics are widely used as bacteriostatic and bactericidal drugs in bacterial infections. besides the respective interactions between the antibiotics and bacteria and between the immune system and bacteria, antibiotics also interact directly with the immune system and have various immunomodulatory effects on phagocytosis, chemotaxis, cytokine production and endotoxine release. in this stu...

BACKGROUND Previous studies have reported that incubation of polymorphonuclear cells (PMN) in uraemic plasma or with different haemodialysis membranes and peritoneal dialysis solutions increases apoptosis in this cell type. In addition, PMN harvested from uraemic patients show a reduced ability to generate superoxide in response to stimuli as well as impaired phagocytosis, chemotaxis and degran...