نتایج جستجو برای: chemical injury
تعداد نتایج: 654282 فیلتر نتایج به سال:
THE purpose of this investigation was to ascertain, primarily from the clinical point of view, whether the vascularization and scarring which follow ocular burns can be inhibited by cortisone, and, if so, whether the use of this drug for this purpose is justified in clinical practice. The experiments reported apply to burns caused by heat; it is proposed to carry out a further series on burns c...
INTRODUCTION Chemical injuries can occur under various circumstances and may cause serious damage to the anterior segment of the eye. OBJECTIVE The aim of the study was to analyse the frequency of chemical injuries treated in a tertiary referral centre. METHODS The medical records of consecutive patients admitted for the chemical injury of the eye to the Clinic for Eye Diseases in Belgrade ...
We have previously suggested that protein kinase C (PKC) contributes to persistent pain in the formalin test. This study compared the effects of pharmacological inhibition of PKC with either GF 109203X or chelerythrine on persistent pain following noxious chemical stimulation with its effects on mechanical hyperalgesia, which develops in the hindpaw contralateral to an injury produced by noxiou...
Incorporation of global climate change (GCC) effects into assessments of chemical risk and injury requires integrated examinations of chemical and nonchemical stressors. Environmental variables altered by GCC (temperature, precipitation, salinity, pH) can influence the toxicokinetics of chemical absorption, distribution, metabolism, and excretion as well as toxicodynamic interactions between ch...
PURPOSE To describe the epidemiology and identify categories of agents involved in chemical eye injuries. METHODS Retrospective case series of consecutive cases of chemical eye injury presenting to the emergency department (ED) at a large eye hospital. Six-hundred and thirty-three patients presented to the ED between January 1, 2006 and December 31, 2009 for treatment of 640 chemical eye inju...
Organ injuries caused by environmental chemical exposures or use of pharmaceutical drugs pose a serious health risk that may be difficult to assess because of a lack of non-invasive diagnostic tests. Mapping chemical injuries to organ-specific histopathology outcomes via biomarkers will provide a foundation for designing precise and robust diagnostic tests. We identified co-expressed genes (mod...
BACKGROUND Work-related burns are common among occupational injuries. Zhejiang Province is an industrial area with a high incidence of chemical burns. We aimed to survey epidemiological features of chemical burns in Zhejiang province to determine associated factors and acquire data for developing a strategy to prevent and treat chemical burns. METHODS Questionnaires were developed, reviewed a...
Drug-induced liver injury (DILI) is an important clinical problem, which has received more attention in recent decades. It can be induced by small chemical molecules, biological agents, traditional Chinese medicines (TCM), natural medicines (NM), health products (HP), and dietary supplements (DS). Idiosyncratic DILI is far more common than intrinsic DILI clinically and can be classified into he...
this is an observational case series study on penetrating trauma admissions in three teaching hospitals in tehran from 1996 to 1997. in order to describe the epidemiology and determine the ways of improving treatment of penetrating injuries, we selected 410 patients with penetrating injuries and injury severity scores (iss) of more than 7 (the maximum iss is 75) out of 3580 trauma patients, hos...
Extensive research in the last decade has defined that most chronic diseases display dysregulation of multiple cell signaling pathways that have been linked to inflammation. Neuroinflammation is reaction of living nervous tissue to injury. It may be initiated in response to neurological disease. Including infection, traumatic brain injury, toxic metabolites and autoimmunity. The natural compoun...
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