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접수 : 2007년 8월 23일, 승인 : 2007년 9월 13일 책임저자: 박혜원, 포천중문의대 소아과학교실 Correspondence: Hye Won Park, M.D. Tel : 031)780-5230 Fax : 031)780-5239 E-mail : [email protected] 하 등을 특징으로 하는 드문 질환으로 영아나 어린 소아의 급성 신부전의 가장 흔한 원인이다 1, 2) . 미세혈관병증 용혈성 빈혈의 성상은 파편이 된 적혈구(schistocytes)가 말초혈액 도말 검사에 서 관찰되고 혈청 lactate dehydrogenase(LDH), 유리 혈색소와 망상 적혈구가 증가하며, 대개의 경우 혈소판 수치는 60,000/ mm 3 이하로 감소한다 1, 3) . 임상 증상과 예후...

We investigated ADAMTS13 activity as well as the ADAMTS13 gene mutation in children with hemolytic uremic syndrome (HUS). Eighteen patients, including 6 diarrhea- negative (D-HUS) and 12 diarrhea-associated HUS (D+HUS) patients, were evaluated. The extent of von Willebrand factor (VWF) degradation was assayed by multimer analysis, and all exons of the ADAMTS13 gene were PCR-amplified using Taq ...

T paper describes the use of multiple-objective decision analysis to qualitatively and quantitatively assess the quality of an endangered watershed and guide future efforts to improve the quality of the watershed. The Upham Brook Watershed is an urban watershed that lies at the interface of declining inner-city Richmond, Virginia, and growth-oriented Henrico County. A section of stream within t...

one of the most important hydrological time series task is to determine if there is any trend in the data and how to achieve stationarity when there is nonstationarity behavior in data. detecting trend and stationarity in hydrological time series may help us to understand the possible links between hydrological processes and global climate changes. in this study yearly, monthly and daily stream...

In this correspondence, we point out two typographical errors in Chai and Tjhung’s paper and we offer the correct formula of the unified Laguerre polynomial-seriesbased cumulative distribution function (cdf) for small-scale fading distributions. A Laguerre polynomial-series-based cdf formula for non-central chi-square distribution is also provided as a special case of our unified cdf result.

Early infantile epileptic encephalopathy (EIEE)-associated mutations in MUNC18-1 cause Munc18-1 misfolding and cellular aggregation. In this issue, Chai et al. (2016. J. Cell Biol http://dx.doi.org/10.1083/jcb.201512016) find that Munc18-1 is a molecular chaperone for α-synuclein and that aggregated Munc18-1 EIEE-causing mutants promote α-synuclein aggregation.

Uncovering hidden determinants of health Jeanne Chai et al. (331–339) study the association between child growth and violence in the home. Transforming society for better health outcomes Cicely Marston et al. (376–382) explain why community participation is crucial. Towards fair assessments Laura Frost et al. (393–395) explain why many voices are needed to understand health and development issues.

Correction: Zika virus has oncolytic activity against glioblastoma stem cells Zhe Zhu, Matthew J. Gorman, Lisa D. McKenzie, Jiani N. Chai, Christopher G. Hubert, Briana C. Prager, Estefania Fernandez, Justin M. Richner, Rong Zhang, Chao Shan, Eric Tycksen, Xiuxing Wang, Pei-Yong Shi, Michael S. Diamond, Jeremy N. Rich, and Milan G. Chheda Vol. 214, No. 10, October 2017. https://doi.org/10.1084/...