Immunoglobulin G4-related disease (IgG4-RD) is a systemic disease, and lymphadenopathy is frequently observed in these patients. Among the 5 subtypes of IgG4-related lymphadenopathy, progressively transformed germinal centers (PTGC)-type IgG4-related lymphadenopathy possesses a unique characteristic that differentiates it from the other 4 subtypes. Here, we report on a rare case of PTGC-type Ig...

Rosai-Dorfman disease (RDD) also known as sinus histiocytosis with massive lymphadenopathy is a rare disorder of histiocytes characterized histologically by intracellular engulfment lymphocytes. It may occur in any age group, but most commonly seen children and young adults. painless, bilateral cervical lymphadenopathy. In approximately one-third patients it can variety extranodal sites where h...

Patients presenting with long standing huge multinodular goiters may present with multiple nodules in the lateral neck, sometime it is very difficult to differentiate thyroid nodules from cervical lymphadenopathy on clinical, radiological and histological evaluation. If patients present with recurrence after surgery for benign thyroid nodules, very rarely they may be associated with thyroid imp...

Cervical lymphadenopathy is a common presentation of nasopharyngeal carcinoma (NPC). It can be present in the classical location of the level II or VI lymph nodes or at any other levels of the lymph nodes in the neck. NPC should be suspected when a patient presents with cervical lymphadenopathy and conductive hearing loss. A thorough endoscopic assessment of the nasopharynx should be performed ...

A 52-year-old male with a history of Human Immunodeficiency Virus (HIV) infection presented with acute renal failure, hypercalcemia, anemia, and cervical lymphadenopathy. Serum protein electrophoresis demonstrated an IgG kappa monoclonal protein and bone scan demonstrated multiple lytic bone lesions. Given patient history/clinical presentation of HIV infection and cervical lymphadenopathy, diff...

Persistent cervical and axillary lymphadenopathy is a common occurrence encountered in clinics across Asian countries. The commonest presentation in young population is secondary to infections of which extrapulmonary tuberculosis tops the list. Occasionally, one encounters neoplastic lesions such as lymphomas.1 In adults, these aberrant swelling warrant exclusion of metastatic malignant disease...

UNLABELLED Kikuchi-Fujimoto (KD) disease is the rare differential diagnoses of chronic cervical lymphadenopathy of unknown etiology. The findings of histopathology may be overlapping, in such condition immunohistochemistry has a definite role to play. Since Tubercular lymphadenopathy is the commonest cause for chronic cervical lymphadenopathy in developing and tropical country like India. Occas...

A 16-year-old male presented to the Emergency Department with a painful 3 × 3 cm left-sided neck swelling six hours following blunt trauma to the neck from a heavy swinging door. A CT angiogram was performed which revealed a large haemorrhagic lymph node as well as generalised cervical lymphadenopathy. The patient was eventually diagnosed with infectious mononucleosis. This case report describe...

We report the case of a 6-year-old male with fever, left maxillofacial swelling, cervical and mediastinal masses, and lymphadenopathy who developed respiratory failure and shock caused by tracheal compression and superior vena cava reflux disorder. The initial diagnosis was maxillary sinus, cervical, and mediastinal abscesses. Initial treatments included maxillary sinus abscess resection, neck ...

leishmaniasis is an endemic parasitic disease in iran. this paper reports the case of a 5-yr-old boy who presented with multiple isolated cervical lymphadenopathy for several months with no history of fever and no signs or symptoms. in an excisional lymph node biopsy, leishmania parasites were histologically detected. thus, leishmaniasis should be included in the differential diagnosis of isola...