نتایج جستجو برای: certolizumab pegol

تعداد نتایج: 885  

2011
Patricia Guyot Peter Taylor Robin Christensen Louisa Pericleous Coralie Poncet Maximilian Lebmeier Pieter Drost Gert Bergman

INTRODUCTION The goal of this study was to compare the efficacy in terms of Health Assessment Questionnaire change from baseline (HAQ CFB), 50% improvement in American College of Rheumatology criterion (ACR-50) and Disease Activity Score in 28 joints (DAS28) defined remission (< 2.6) between abatacept and other biologic disease modifying anti-rheumatic drugs (DMARDs) in patients with rheumatoid...

Journal: :American Journal of Ophthalmology Case Reports 2020

2014
Sriya Ranatunga Anne V Miller

The axial spondyloarthropathies are a group of chronic inflammatory diseases that predominantly affect the axial joints. This group includes ankylosing spondylitis and nonradiographic axial spondyloarthropathy. While the pathogenesis of axial spondyloarthropathies is not clear, immunologically active tissues primarily include the entheses, ie, the areas where ligaments, tendons, and joint capsu...

Journal: :Expert opinion on biological therapy 2012
Sarah Horton Ceara Walsh Paul Emery

INTRODUCTION Improved understanding of the pathogenesis of rheumatoid arthritis (RA), and subsequent development of targeted therapies, have greatly advanced the management of this chronic inflammatory disease. The aim of treatment is a state of clinical remission. Certolizumab pegol (CZP) is a novel pegylated TNF alpha inhibitor (TNFi) therapy and is the focus of this review. AREAS COVERED C...

Journal: :Expert opinion on biological therapy 2013
Marc Ferrante Séverine Vermeire Paul Rutgeerts

INTRODUCTION The introduction of antibodies directed against tumour necrosis factor (anti-TNF) has dramatically changed the concept of treating patients with Crohn's disease (CD). Unfortunately, the long-term efficacy of anti-TNF agents may be hampered by immunogenicity. The availability of more anti-TNF agents in the therapeutic armamentarium would therefore be of great benefit in patients loo...

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