Lupus anticoagulants are circulating autoantibodies, primarily directed against phospholipids, that prolong the partial thromboplastin time. They have been previously associated with systemic arterial and venous thrombosis and arterial stroke, but not with cerebral venous thrombosis. We describe 2 young patients with cerebral venous thrombosis documented by intravenous digital subtraction angio...

In this paper, we describe the case of recurrent cerebral venous sinus thrombosis in a patient with increased factor VIII activity, lipoprotein (a) level, and leukocytosis. In addition, we discuss the diagnosis of increased factor VIII activity in patients with cerebral venous thrombosis. With regard to therapy, studies need to be done to establish the duration of therapy with phenprocoumon and...

BACKGROUND AND PURPOSE Cerebral venous thrombosis is a rare entity that can be difficult to manage. Most patients with cerebral sinus thrombosis recover after treatment with heparin, but a subgroup of severe cerebral venous sinus thrombosis has a poor prognosis. Those patients may benefit from intrasinus thrombolysis. The purpose of this research was to carry out a retrospective analysis of pat...

The association of spontaneous intracranial hypotension with cerebral venous sinus thrombosis is rare. We report here a case of extensive cerebral venous sinus thrombosis involving three sinuses following spontaneous intracranial hypotension. The patient presented no other thrombotic risk factors except for spontaneous intracranial hypotension. This case adds to the evidence that spontaneous in...

OBJECTIVE To investigate recanalisation in the first 12 months after cerebral venous thrombosis. METHODS 33 consecutive patients presenting with cerebral venous thrombosis were enrolled in the study. Diagnosis was made by magnetic resonance imaging (MRI) and magnetic resonance venography (MRV) or catheter angiography. Patients were initially treated with intravenous heparin. Warfarin was give...

BACKGROUND Isolated thrombosis of the deep cerebral venous system is very rare and is associated with a poor prognosis. Antithrombin III (AT III) deficiency is a disorder of hypercoagulability associated with deep venous thrombosis and recurrent pulmonary emboli. We report a case of an 18-year-old man who presented with spontaneous thrombosis of the deep cerebral veins and straight dural sinus ...

Four cases, two infants and two adults, of extensive thrombosis of the intracranial venous sinuses are described. Infarction of the brain had occurred in three cases. The first two cases presented as diabetic coma. The third case has been included to represent primary puerperal cerebral venous thrombosis. Extensive venous sinus thrombosis was seen at post-mortem examination in the fourth case, ...

INTRODUCTION Seizure involves less than 1% of pregnancies; however it is associated with increased maternal and fetal complications. Cerebral venous sinus thrombosis is a rare, but potentially life-threatening cause of seizure during pregnancy, presenting primarily as seizure in 12% - 31.9% of cases. Pregnancy and puerperium are known as the risk factors of cerebral venous sinus thrombosis. C...

chronic venous thromboses were also more common than acute thrombosis. Squizzato et al.1 reported 13 cases of acute cerebral sinus venous thrombosis associated with thyroid disease. The most common etiology of hyperthyroidism was Graves--Basedow disease, and a hypercoagulability state and even vascular compression in the event of large goiter were suggested as a pathogenetic mechanism. In the r...

BACKGROUND AND PURPOSE Cerebral venous thrombosis is characterized by its clinical pleomorphism and pathogenetic variability. We studied 67 patients with cerebral venous thrombosis associated with pregnancy and puerperium and compared them with 46 other cases unrelated to obstetric causes to disclose differences in their clinical presentation, neuroradiological findings, clinical course, and pr...