background: an imbalance of the cerebrovascular response during functional activation of the brain has been postulated as a factor in the pathophysiology of migraine. the purpose of this study was to determine the transcranial doppler sonography (tds) diagnostic value for the cerebral flow velocity changes in the interictal phase of classic migraine. methods: this study was carried out on 46 pa...

The mechanisms underlying cerebral vasodilatation during hypercapnia are not fully understood. To examine the role of nerves and prostaglandins in the regulation of basal blood flow and in hypercapnia-induced vasodilatation in the cerebral blood vessels of rabbit.Cerebral blood flow was measured by laser Doppler flow-meter in 18 NZW rabbits anesthetized with sodium pentobarbital.  Tetrodetoxin ...

background traditional digital subtraction angiography (dsa) is currently the gold standard diagnostic method for the diagnosis and evaluation of cerebral arteriovenous malformation (avm) and dural arteriovenous fistulas (davf). objectives the aim of this study was to analyze different less invasive magnetic resonance angiography (mra) images, time-resolved mra (tr-mra) and three-dimensional ti...

background & objectives: ischemic stroke is the third leading cause of death and disability in most of the human societies. there is no effective treatment due to complexity of the pathophysiological mechanisms. today, more researches are designed to introduce involving factors and new treatment strategies in brain ischemia. the objective of this study is to introduce an experimental model of t...

EVEN BEFORE the endothelium-derived relaxing factor (EDRF) was known to be nitric oxide (NO), it was recognized that it could be inactivated by the radical superoxide (O2 · ) (16). Once the EDRF was identified as NO, the chemistry underlying this phenomenon was obvious. Both NO and O2 · are radicals, and rapidly react with one another to form the strong oxidant peroxynitrite, which ultimately d...

background and purpose: speech intelligibility refers to how speech is understandable by listeners.  this study examined speech intelligibility in children (persian native speakers) with spastic cerebral palsy aged 8-12 years old. materials and methods: a cross-sectional study was performed in 31dysarthric students (….. boys and …..girls)  in tehran, 2014. a list of words and sentences were pre...

abstract background: nowadays, caregivers’ general health has an influential impact on patients’ and attendants’ education as well as the management of chronic diseases. this study aimed to design, develop and evaluate an android application based on a user-led approach to educate caregivers of children with cerebral palsy. methods: to conduct this applied developmental study, we first assessed...

cerebral sinovenous thrombosis (csvt) is increasingly diagnosed in neonates. despite many studies which have addressed diagnosis and management of pediatric csvt, diagnosis of cvsd in neonates is difficult. a female neonate born by natural vaginal delivery was diagnosed with csvt after initiation of seizure. the seizure was stabilized and after performing diagnostic tests, the diagnosis of csvt...

Background: An imbalance of the cerebrovascular response during functional activation of the brain has been postulated as a factor in the pathophysiology of migraine. The purpose of this study was to determine the transcranial doppler sonography (TDS) diagnostic value for the cerebral flow velocity changes in the interictal phase of classic migraine. Methods: This study was carried out on 46 pa...