Abstract Introduction Central sleep apnea (CSA) is a rare form of disordered breathing with repeated apneic episodes absence associated respiratory effort. CSA due to medication well described in literature opiate therapy. Baclofen which gamma-aminobutyric acid-B agonist muscle relaxant properties has been implicated CSA. We present case likely chronic baclofen use. Patient underwent polysomnog...

Abstract Introduction Obstructive sleep apnea (OSA) is well known to often improve with non-supine positioning as opposed supine positioning. The prevalence of OSA that may on proper 50-60% and the appears when disappears 25-30%. Sleeping in a lateral thought reduce pressure airway, shift directional effect gravity airway structures, counteract physiologic genioglossus collapse occurs supine. O...

In the first part of this 2-part review, we provided a synopsis of the cardiovascular effects of normal sleep and an overview of the diagnostic, pathophysiological, and therapeutic implications of obstructive sleep apnea (OSA) in the setting of heart failure (HF). In this second part, we turn our attention to central sleep apnea (CSA), commonly referred to as Cheyne-Stokes respiration. This bre...

Two obese patients with sleep apnea syndrome were administered chlormadinone acetate (CMA), a synthetic progesterone, known as a potent respiratory stimulant to augment load compensation response as well as CO2 chemosensitivity. Before CMA administration, both cases showed normal chemosensitivity of hypoxic and hypercapnic ventilatory responses (HVR and HCVR) at daytime, although marked oxygen ...

Background—Obstructive sleep apnea (OSA) and central sleep apnea are common in patients with heart failure. We hypothesized that in such patients, severity of OSA is related to overnight rostral leg fluid displacement and increase in neck circumference, severity of central sleep apnea is related to overnight rostral fluid displacement and to sleep PCO2, and continuous positive airway pressure a...

BACKGROUND Obstructive sleep apnea (OSA) and central sleep apnea are common in patients with heart failure. We hypothesized that in such patients, severity of OSA is related to overnight rostral leg fluid displacement and increase in neck circumference, severity of central sleep apnea is related to overnight rostral fluid displacement and to sleep Pco(2), and continuous positive airway pressure...

As a follow-up to a previous assessment of complications of sleep-disturbed breathing in 265 patients, we have reevaluated measures of sleepiness and hypertension in patients with obstructive sleep apnea (OSA) (n = 518), central sleep apnea (n = 50), and subclinical sleep-disordered breathing (SDB) (n = 107). Both subjective and objective (multiple sleep latency test [MSLT]) measures indicated ...

www.thoracic.org C LI P A N D C O P Y What is Sleep Disordered Breathing (SDB)? SDB is a general term used to describe various different abnormalities in breathing pattern which occur during sleep, including obstructive and central sleep apnea. Obstructive sleep apnea (OSA) is a common disorder which affects roughly 10% of the US population and approximately 1/3 of people with congestive heart ...