nigella sativa (ns) (ranunculaceae family) is generally utilized as a therapeutic plant all over the world. the seeds of the plant have a long history of use in different frameworks of medicines and food. in islamic literature, it is considered as one of the greatest forms of therapeutics. it has been widely used to treat nervous system diseases such as memory impairment, epilepsy, neurotoxicit...

     Multiple sclerosis (MS) is an inflammatory, demyelinating, neurodegenerative disorder of the central nervous system (CNS) of unknown etiology. Isolated oculomotor nerve palsy is found rarely in children with MS. We present a case of MS in 10-year-old boy, who had bilateral ptosis associated with medial gaze restriction. The extraocular muscle examination demonstrated bilateral adduction pa...

multiple sclerosis (ms) is an autoimmune disease of the central nervous system (cns) characterized by inflammatory and neurodegenerative processes. one of its pathophysiological hallmarks is demyelination, a consequence of oligodendroglial cell death leading supply shortfall and missing electrical insulation to axons. demyelination induced consequences on neuronal network activity and subsequen...

neurotrauma is one of the main medical problems that affect considerable number of population especially young persons in all countries. neurotrauma not only is a serious threat for life but also creates various disabilities and consequently imposes large costs to society. following central nervous system (cns) injury, tissue damage occurs via primary and secondary mechanisms. despite many atte...

context patients with hepatic dysfunction suffer from many problems and associated complications in organs other than the liver. therefore, it is very important to investigate the effects of different drugs in the treatment of these patients. due to the high consumption of non-steroidal anti-inflammatory drugs (nsaids), studying the effects of these drugs in patients with hepatic dysfunction is...

besides being a metabolite of nucleotides like atp, adenosine is a mediator of neuronal function in the central nervous system. its actions are mediated by at least three extracellular receptors. in this review different aspects of adenosine such as biosynthesis, release, inactivation and its receptors are discussed. it also covers pre- and postsynaptic effects as well as postreceptor mechanism...

Treating Central Nervous System (CNS) neuro-inflammational disorders is of great importance. A key aspect of this treatment includes regulation of Cell-Mediated and humoral immune systems. Previous treatment mostly consisted of systemic immunosuppressive drugs. In addition to having adverse side effects, these drugs were also inefficient, such as methotrexate- Cyclophosphamide-Azathioprine. Rec...

The heart of the crustaceans has its own pacemaker neurons inside the heart, which are composed of 9 neurons. The neurons receive innervations of only three kinds of axons originated from the central nervous system; one pair of inhibitory and two pairs of acceleratory axons. Thus, in terms of the neural cardiac control from higher center, this system may have much more simplistic operation comp...

The heart of the crustaceans has its own pacemaker neurons inside the heart, which are composed of 9 neurons. The neurons receive innervations of only three kinds of axons originated from the central nervous system; one pair of inhibitory and two pairs of acceleratory axons. Thus, in terms of the neural cardiac control from higher center, this system may have much more simplistic operation comp...

Several protozoan and helminth parasites can affect the central nervous system. In some cases the parasite may have a tropism for the central nervous system (CNS) and this represents the primary affect of the pathogen. In many cases, though, the pathogen does not exhibit a specific tropism for the CNS and affects many other organs and tissues. However, the symptoms associated with the invasion ...