Background: Due to limited clinical data in pediatric-type sarcomas (rhabdomyosarcoma, Ewing's sarcoma, PNET, and desmoplastic small round-cell tumor), the aim of this study was to evaluate the demographic characteristics and identifying prognostic factors for survival. Materials and Methods: We retrospectively reviewed 110 patients with pediatric-type sarcomas. Overall and disease free surviva...

objective: vitrification has been shown as one of the most effective methods of cryopreservation for mammalian embryos. however, there is no consensus which stage of embryonic development is the most appropriate for vitrification with subsequent maximal development after thawing. this study was carried out to explore and compare the effect(s) of vitrification on mouse 2-cell, 4-cell, 8-cell, mo...

introduction: this study was designed to compare the effects of three vitrification procedures [conventional (c), open pulled straw (ops) and closed pulled straw (cps)] on morphological survival of two-cell mouse embryos and their subsequent development to hatched blastocysts. material and methods: two-cell mouse embryos were divided into four groups, control (194), ops (150), cps (155) and c (...

Background: Gastric cancer is among the most common malignancies in certain parts of the world, such as northwest Iran. miRNAs are small and single-stranded noncoding RNAs with about 19-23 nucleotides. Several studies have shown that miRNAs play important roles in gastric tumorigenesis. The aim of this study was to determine the effect of miRNA-1266-5p repression on the cell survival and altera...

Background: We explored survival of skin cancer and its determinants in Kurdistan province of Iran. Methods: In a retrospective cohort design, we identified all registered skin cancer patients in Kurdistan Cancer Registry from year 2000 to 2009. Information on time and cause of death were obtained from Registrar’s office and information on type, stage and anatomic locations were extracted fr...

allogeneic hematopoietic stem cell transplantation (hsct) is the most effective therapy to prevent relapse in acute lymphocytic leukemia (all). this benefit is affected by non-relapse mortality (nrm) due to complications such as graft versus host disease (gvhd). a new approach in analyzing time-dependent covariates in competing risks is landmark analysis. so, the aim of this study is to evaluat...

background: rhabdomyosarcoma is a rare malignant soft tissue sarcoma and the most common sarcoma of childhood. the purpose of this study was to investigate the distribution of age and sex of patients, pathological subtypes and to determine the role of staging and classification of rms on treatment outcome. materials and methods: this retrospective study included patients who diagnosed with rms ...

background: endometriosis is a common chronic inflammation which leads to infertility and chronic pelvic pain in affected women. secretory phospholipase a2 type iia (spla2iia) is an acute phase reactant that is markedly increased in inflammatory disorders. objective: to assess the effects of ω-3 and ω-6 polyunsaturated fatty acids (pufas) administration in endometrial cells culture on spla2iia ...

Background: Radiotherapy and adjuvant androgen deprivation therapy have historically been the first treatment choices for prostate cancer but treatment resistance often limits the capacity to effectively manage the disease. Therefore, alternative therapeutic approaches are needed. Here, the efficacies of radiotherapy and targeting the pro-survival cell signaling components epidermal growth fact...