Lithium is the main therapeutic agent for the treatment of bipolar disorders but nerve cells are not the sole target of this drug. Indeed, lithium has been reported to target numerous cell types and to affect cell proliferation, differentiation and death. Lithium targets a variety of enzymes among which there is GSK-3beta and a number of cell responses elicited by lithium are mediated by the Wn...

Abstract Introduction: Non-melanoma scalp skin cancers (NMSCs) including squamous cell carcinomas (SCCs) and basal cell carcinomas (BCCs) are common. To manage such cancers, especially SCCs, more attention should be paid to their invasive characteristics. Mortality surveillance of SCCs and BCCs of scalp helps to choose proper approaches. Methods: The current retrospective, descriptive study w...

Abstract Introduction: Non-melanoma scalp skin cancers (NMSCs) including squamous cell carcinomas (SCCs) and basal cell carcinomas (BCCs) are common. To manage such cancers, especially SCCs, more attention should be paid to their invasive characteristics. Mortality surveillance of SCCs and BCCs of scalp helps to choose proper approaches. Methods: The current retrospective, descriptive study w...

There is some evidence that leukocytosis without infection is associated with increased hospital mortality, but data in this regard are very incomplete. This study was designed to investigate the relationship between leukocytosis at the time of admission and mortality among patients hospitalized in general wards. During July to Nov 2004, all deceased patients who had a white blood cell (WBC) co...

The link between influenza virus (IV) viral load (VL) in respiratory samples and disease severity is not clearly established. This study was designed to assess IV-VL from flu patients admitted intensive care unit (ICU). Patients ICU for IV infection, as documented by RT-PCR, with failure were included the during 5 flu-seasons (2014–2018). Routine management parameters recorded. Real-time amplif...

Background: Lung cancer is a leading cause of cancer-related mortality worldwide. The purpose our meta-analysis was to assess the risk factors for brain metastases (BM) in patients with non-small cell lung (NSCLC).

In cancer, there is uncontrolled cell division, which results in invasion and metastasis. Carcinomas are a significant cause of mortality worldwide. Recently, radiotherapy chemotherapy the primary treatment measures that being used to destroy cancer cells.

Six hundred 1-d-old male broilers (Ross 308) were assigned to four experimental groups; each was composed of 5 floor pen replications of 30 birds including control (no enalapril), 15, 30 and 60 ppm enalapril in the drinking water. From d 21 to 49, all the chicks were exposed to low ambient temperature to induce ascites. Mortalities were inspected to determine the cause of death and diagnose of ...

cardiovascular disease remains the leading cause of morbidity and mortality in the united states and europe. in recent years, the understanding that regenerative processes exist at the level of the myocardium, has placed stem cell research at center stage in cardiology. a stem cell is a cell that has the ability to divide (self replicate) for indefinite periods often throughout the life of the ...