Given the extensive application of carbon nanotubes (CNTs) in biomedical fields, there is increasing concern regarding unintentional health impacts. Research into safe usage is therefore increasingly necessary. This study investigated the responses of the mouse brain to single-walled CNTs (SWCNTs) delivered via intraperitoneal (IP) injection and compared these results with the previous study wh...

Background: The application of mesenchymal stem cells in the healing of chronic wounds is one of the most challenging issues in cell therapy. The present study investigated the efficacy of intradermal injection of umbilical cord Wharton's Jelly-derived mesenchymal stem cells in diabetic wound healing using ultrasound imaging in an animal model. Methods: During this experimental laboratory stud...

In this study, a new flow injection analysis (FIA) based on microfluidic cell (MFC) with sample capacity of 40 µL is described. A Tungsten lamp directs light from typical 2100P Portable Turbidimeter apparatus into quartz through round sidewall aperture 2.0 mm and emerges the identical opposite side cell, where photodiode array (light detector) detects passing light. When compared to traditional...

Effector T-cell access to tumor tissue is a limiting step for clinical efficacy of antigen-specific T cell-based immunotherapies. Ectopic mouse tumor models, in which a subcutaneously (s.c.) implanted tumor is treated with s.c. or intramuscular therapeutic immunization, may not be optimal for targeting effector T cells to an organ-borne tumor. We used an orthotopic renal carcinoma model to eval...

BACKGROUND Development of influenza vaccines capable of inducing broad protection against different virus subtypes is necessary given the ever-changing viral genetic landscape. Previously, we showed that vaccination with whole inactivated virus (WIV) induces heterosubtypic protection against lethal virus infection in mice. Whole inactivated virus-induced cross-protection was found to be mediate...

Cell delivery via the retrograde coronary route boasts less vessel embolism, myocardial injury, and arrhythmogenicity when compared with those via antegrade coronary administration or myocardial injection. However, conventional insertion into the coronary sinus and consequent bleeding complication prevent its application in small animals. To overcome the complication of bleeding, we described a...

in this literature, a combined method has been employed to simultaneously reducesmoke (soot) and oxide of nitrogen (nox) and maintain the performance parameters of dieselengine. this includes creating an air jet by designing an air-cell inside the piston body, advancedinjection timing and using cold exhaust gas recirculation. the tested engine was an mt4.244engine that worked as natural aspirat...

PURPOSE To study the effect of injection bevacizumab on iris neovascularization (NVI) and angle neovascularization (NVA) and compare its efficacy in terms of visual outcome, NVI, NVA, and intraocular pressure (IOP) control between intracameral, intravitreal, and combined use. MATERIALS AND METHODS This was a prospective study conducted at a tertiary center for patients of neovascular glaucoma...