Vitex agnus castus L. (VAC) [Verbenaceae] is a deciduous shrub that is native to Mediterranean Europe and Central Asia. Traditionally, VAC fruit extract has been used in the treatment of many female conditions, including menstrual disorders (amenorrhoea, dysmenorrhoea), premenstrual syndrome (PMS), corpus luteum insufficiency, hyperprolactinaemia, infertility, acne, menopause and disrupted lact...

BACKGROUND Polycystic ovary syndrome (PCOS) is a prevalent, complex endocrine disorder characterised by polycystic ovaries, chronic anovulation and hyperandrogenism leading to symptoms of irregular menstrual cycles, hirsutism, acne and infertility. Evidence based medical management emphasises a multidisciplinary approach for PCOS, as conventional pharmaceutical treatment addresses single sympto...

d-galactose induces pancreatic disorder along with aging mouse model. vitex agnus-castus (vac) has potential pancreatic protective effect. hence, this study was designed to evaluate the hypoglycemic and pancreas protective effects of vac hydroalcoholic extract in d-galactose-induced aging female mice. in the present experimental study, 72 adult female naval medical research institute (nmri) mic...

Background. Primary dysmenorrhea (PD) is one of the most common types gynecological pathology and observed in 31–52% young women, 10% them pain so intense that leads to disability. In pathogenesis PD consider a representative eicosanoids— thromboxane A2 with pronounced vasoconstrictor effect. The article presents results clinical hormonal examination women developed on this basis method treatme...